Low levels of K(ATP) channel activation decrease excitability and contractility of urinary bladder.
Petkov GV, Heppner TJ, Bonev AD, Herrera GM, Nelson MT.
Petkov GV, et al. Among authors: nelson mt.
Am J Physiol Regul Integr Comp Physiol. 2001 May;280(5):R1427-33. doi: 10.1152/ajpregu.2001.280.5.R1427.
Am J Physiol Regul Integr Comp Physiol. 2001.
PMID: 11294764
Free article.
ZD-6169 and levcromakalim at 1.02 and 2.63 microM, respectively, caused half-maximal activation (K1/2) of K(ATP) currents in single UBSM cells (see Heppner TJ, Bonev A, Li JH, Kau ST, and Nelson MT. Pharmacology 53: 170-179, 1996). In contrast, much lower concentrat …
ZD-6169 and levcromakalim at 1.02 and 2.63 microM, respectively, caused half-maximal activation (K1/2) of K(ATP) currents in single UBSM cel …