Qian L - Search Results

1

Substance P enhances microglial density in the substantia nigra through neurokinin-1 receptor/NADPH oxidase-mediated chemotaxis in mice.

Wang Q, Oyarzabal E, Wilson B, Qian L, Hong JS. Wang Q, et al. Among authors: qian l. Clin Sci (Lond). 2015 Oct 1;129(8):757-67. doi: 10.1042/CS20150008. Epub 2015 Jun 22. Clin Sci (Lond). 2015. PMID: 26223840 Free PMC article.

2

Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.

Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS. Zhang D, et al. Among authors: qian l. J Neuroinflammation. 2008 May 28;5:21. doi: 10.1186/1742-2094-5-21. J Neuroinflammation. 2008. PMID: 18507839 Free PMC article.

3

Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases.

Wang Q, Chu CH, Oyarzabal E, Jiang L, Chen SH, Wilson B, Qian L, Hong JS. Wang Q, et al. Among authors: qian l. Glia. 2014 Dec;62(12):2034-43. doi: 10.1002/glia.22724. Epub 2014 Jul 17. Glia. 2014. PMID: 25043383 Free PMC article.

4

Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase.

Wang Q, Chu CH, Qian L, Chen SH, Wilson B, Oyarzabal E, Jiang L, Ali S, Robinson B, Kim HC, Hong JS. Wang Q, et al. Among authors: qian l. J Neurosci. 2014 Sep 10;34(37):12490-503. doi: 10.1523/JNEUROSCI.2238-14.2014. J Neurosci. 2014. PMID: 25209287 Free PMC article.

5

Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models.

Wang Q, Qian L, Chen SH, Chu CH, Wilson B, Oyarzabal E, Ali S, Robinson B, Rao D, Hong JS. Wang Q, et al. Among authors: qian l. Brain. 2015 May;138(Pt 5):1247-62. doi: 10.1093/brain/awv034. Epub 2015 Feb 25. Brain. 2015. PMID: 25716193 Free PMC article.

6

Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase.

Qian L, Block ML, Wei SJ, Lin CF, Reece J, Pang H, Wilson B, Hong JS, Flood PM. Qian L, et al. J Pharmacol Exp Ther. 2006 Oct;319(1):44-52. doi: 10.1124/jpet.106.106351. Epub 2006 Jun 28. J Pharmacol Exp Ther. 2006. PMID: 16807359

7

Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity.

Qian L, Tan KS, Wei SJ, Wu HM, Xu Z, Wilson B, Lu RB, Hong JS, Flood PM. Qian L, et al. J Immunol. 2007 Jul 15;179(2):1198-209. doi: 10.4049/jimmunol.179.2.1198. J Immunol. 2007. PMID: 17617613

8

MAC1 mediates LPS-induced production of superoxide by microglia: the role of pattern recognition receptors in dopaminergic neurotoxicity.

Pei Z, Pang H, Qian L, Yang S, Wang T, Zhang W, Wu X, Dallas S, Wilson B, Reece JM, Miller DS, Hong JS, Block ML. Pei Z, et al. Among authors: qian l. Glia. 2007 Oct;55(13):1362-73. doi: 10.1002/glia.20545. Glia. 2007. PMID: 17654704

9

Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase.

Qian L, Xu Z, Zhang W, Wilson B, Hong JS, Flood PM. Qian L, et al. J Neuroinflammation. 2007 Sep 19;4:23. doi: 10.1186/1742-2094-4-23. J Neuroinflammation. 2007. PMID: 17880684 Free PMC article.

10

NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation.

Qian L, Gao X, Pei Z, Wu X, Block M, Wilson B, Hong JS, Flood PM. Qian L, et al. Parkinsonism Relat Disord. 2007;13 Suppl 3:S316-20. doi: 10.1016/S1353-8020(08)70023-3. Parkinsonism Relat Disord. 2007. PMID: 18267257

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