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Engrailed-2 (En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behavior.
Genestine M, Lin L, Durens M, Yan Y, Jiang Y, Prem S, Bailoor K, Kelly B, Sonsalla PK, Matteson PG, Silverman J, Crawley JN, Millonig JH, DiCicco-Bloom E. Genestine M, et al. Among authors: silverman j. Hum Mol Genet. 2015 Oct 15;24(20):5805-27. doi: 10.1093/hmg/ddv301. Epub 2015 Jul 28. Hum Mol Genet. 2015. PMID: 26220976 Free PMC article.
Sociability and motor functions in Shank1 mutant mice.
Silverman JL, Turner SM, Barkan CL, Tolu SS, Saxena R, Hung AY, Sheng M, Crawley JN. Silverman JL, et al. Brain Res. 2011 Mar 22;1380:120-37. doi: 10.1016/j.brainres.2010.09.026. Epub 2010 Sep 21. Brain Res. 2011. PMID: 20868654 Free PMC article.
Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication.
Bozdagi O, Sakurai T, Papapetrou D, Wang X, Dickstein DL, Takahashi N, Kajiwara Y, Yang M, Katz AM, Scattoni ML, Harris MJ, Saxena R, Silverman JL, Crawley JN, Zhou Q, Hof PR, Buxbaum JD. Bozdagi O, et al. Among authors: silverman jl. Mol Autism. 2010 Dec 17;1(1):15. doi: 10.1186/2040-2392-1-15. Mol Autism. 2010. PMID: 21167025 Free PMC article.
Automated three-chambered social approach task for mice.
Yang M, Silverman JL, Crawley JN. Yang M, et al. Curr Protoc Neurosci. 2011 Jul;Chapter 8:Unit 8.26. doi: 10.1002/0471142301.ns0826s56. Curr Protoc Neurosci. 2011. PMID: 21732314 Free PMC article.
Low sociability in BTBR T+tf/J mice is independent of partner strain.
Yang M, Abrams DN, Zhang JY, Weber MD, Katz AM, Clarke AM, Silverman JL, Crawley JN. Yang M, et al. Physiol Behav. 2012 Dec 5;107(5):649-62. doi: 10.1016/j.physbeh.2011.12.025. Epub 2012 Jan 8. Physiol Behav. 2012. PMID: 22245067 Free PMC article.
2,034 results