Linhardt RJ - Search Results

1

Heparin and related polysaccharides: synthesis using recombinant enzymes and metabolic engineering.

Suflita M, Fu L, He W, Koffas M, Linhardt RJ. Suflita M, et al. Among authors: linhardt rj. Appl Microbiol Biotechnol. 2015 Sep;99(18):7465-79. doi: 10.1007/s00253-015-6821-9. Epub 2015 Jul 29. Appl Microbiol Biotechnol. 2015. PMID: 26219501 Free PMC article. Review.

2

Enzymatic synthesis of heparin related polysaccharides on sensor chips: rapid screening of heparin-protein interactions.

Muñoz E, Xu D, Avci F, Kemp M, Liu J, Linhardt RJ. Muñoz E, et al. Among authors: linhardt rj. Biochem Biophys Res Commun. 2006 Jan 13;339(2):597-602. doi: 10.1016/j.bbrc.2005.11.051. Epub 2005 Nov 17. Biochem Biophys Res Commun. 2006. PMID: 16310167 Free PMC article.

3

Enzymatic synthesis of glycosaminoglycan heparin.

Linhardt RJ, Dordick JS, Deangelis PL, Liu J. Linhardt RJ, et al. Semin Thromb Hemost. 2007 Jul;33(5):453-65. doi: 10.1055/s-2007-982076. Semin Thromb Hemost. 2007. PMID: 17629842 Free PMC article. Review.

4

Recent progress and applications in glycosaminoglycan and heparin research.

Laremore TN, Zhang F, Dordick JS, Liu J, Linhardt RJ. Laremore TN, et al. Among authors: linhardt rj. Curr Opin Chem Biol. 2009 Dec;13(5-6):633-40. doi: 10.1016/j.cbpa.2009.08.017. Epub 2009 Sep 24. Curr Opin Chem Biol. 2009. PMID: 19781979 Free PMC article. Review.

5

E. coli K5 fermentation and the preparation of heparosan, a bioengineered heparin precursor.

Wang Z, Ly M, Zhang F, Zhong W, Suen A, Hickey AM, Dordick JS, Linhardt RJ. Wang Z, et al. Among authors: linhardt rj. Biotechnol Bioeng. 2010 Dec 15;107(6):964-73. doi: 10.1002/bit.22898. Biotechnol Bioeng. 2010. PMID: 20717972 Free PMC article.

6

Control of the heparosan N-deacetylation leads to an improved bioengineered heparin.

Wang Z, Yang B, Zhang Z, Ly M, Takieddin M, Mousa S, Liu J, Dordick JS, Linhardt RJ. Wang Z, et al. Among authors: linhardt rj. Appl Microbiol Biotechnol. 2011 Jul;91(1):91-9. doi: 10.1007/s00253-011-3231-5. Epub 2011 Apr 12. Appl Microbiol Biotechnol. 2011. PMID: 21484210 Free PMC article.

7

Response surface optimization of the heparosan N-deacetylation in producing bioengineered heparin.

Wang Z, Li J, Cheong S, Bhaskar U, Akihiro O, Zhang F, Dordick JS, Linhardt RJ. Wang Z, et al. Among authors: linhardt rj. J Biotechnol. 2011 Dec 10;156(3):188-96. doi: 10.1016/j.jbiotec.2011.08.013. Epub 2011 Sep 10. J Biotechnol. 2011. PMID: 21925548 Free PMC article.

8

Engineering of routes to heparin and related polysaccharides.

Bhaskar U, Sterner E, Hickey AM, Onishi A, Zhang F, Dordick JS, Linhardt RJ. Bhaskar U, et al. Among authors: linhardt rj. Appl Microbiol Biotechnol. 2012 Jan;93(1):1-16. doi: 10.1007/s00253-011-3641-4. Epub 2011 Nov 3. Appl Microbiol Biotechnol. 2012. PMID: 22048616 Free PMC article. Review.

9

High cell density cultivation of a recombinant E. coli strain expressing a key enzyme in bioengineered heparin production.

Restaino OF, Bhaskar U, Paul P, Li L, De Rosa M, Dordick JS, Linhardt RJ. Restaino OF, et al. Among authors: linhardt rj. Appl Microbiol Biotechnol. 2013 May;97(9):3893-900. doi: 10.1007/s00253-012-4682-z. Epub 2013 Jan 15. Appl Microbiol Biotechnol. 2013. PMID: 23318839 Free PMC article.

10

An 'omics approach towards CHO cell engineering.

Datta P, Linhardt RJ, Sharfstein ST. Datta P, et al. Among authors: linhardt rj. Biotechnol Bioeng. 2013 May;110(5):1255-71. doi: 10.1002/bit.24841. Epub 2013 Feb 4. Biotechnol Bioeng. 2013. PMID: 23322664 Review.

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