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JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results.
Uno Y, Kojima H, Omori T, Corvi R, Honma M, Schechtman LM, Tice RR, Beevers C, De Boeck M, Burlinson B, Hobbs CA, Kitamoto S, Kraynak AR, McNamee J, Nakagawa Y, Pant K, Plappert-Helbig U, Priestley C, Takasawa H, Wada K, Wirnitzer U, Asano N, Escobar PA, Lovell D, Morita T, Nakajima M, Ohno Y, Hayashi M. Uno Y, et al. Among authors: beevers c. Mutat Res Genet Toxicol Environ Mutagen. 2015 Jul;786-788:45-76. doi: 10.1016/j.mrgentox.2015.04.010. Epub 2015 Apr 29. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 26212295
Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test.
Bowen DE, Whitwell JH, Lillford L, Henderson D, Kidd D, Mc Garry S, Pearce G, Beevers C, Kirkland DJ; Work conducted at Covance Laboratories Ltd., Harrogate. Bowen DE, et al. Among authors: beevers c. Mutat Res. 2011 May 18;722(1):7-19. doi: 10.1016/j.mrgentox.2011.02.009. Epub 2011 Feb 25. Mutat Res. 2011. PMID: 21356328
Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT).
Speit G, Kojima H, Burlinson B, Collins AR, Kasper P, Plappert-Helbig U, Uno Y, Vasquez M, Beevers C, De Boeck M, Escobar PA, Kitamoto S, Pant K, Pfuhler S, Tanaka J, Levy DD. Speit G, et al. Among authors: beevers c. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:6-12. doi: 10.1016/j.mrgentox.2014.09.006. Epub 2014 Sep 22. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953395
Genotoxicity assessment of the flavouring agent, perillaldehyde.
Hobbs CA, Taylor SV, Beevers C, Lloyd M, Bowen R, Lillford L, Maronpot R, Hayashi SM. Hobbs CA, et al. Among authors: beevers c. Food Chem Toxicol. 2016 Nov;97:232-242. doi: 10.1016/j.fct.2016.08.029. Epub 2016 Sep 1. Food Chem Toxicol. 2016. PMID: 27593899 Free article.
Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell gene mutation assays) and integration with somatic cell testing.
Marchetti F, Aardema MJ, Beevers C, van Benthem J, Godschalk R, Williams A, Yauk CL, Young R, Douglas GR. Marchetti F, et al. Among authors: beevers c. Mutat Res Genet Toxicol Environ Mutagen. 2018 Aug;832-833:7-18. doi: 10.1016/j.mrgentox.2018.05.021. Epub 2018 May 29. Mutat Res Genet Toxicol Environ Mutagen. 2018. PMID: 30057023 Free article.
174 results