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The C-terminal domain of Nrf1 negatively regulates the full-length CNC-bZIP factor and its shorter isoform LCR-F1/Nrf1β; both are also inhibited by the small dominant-negative Nrf1γ/δ isoforms that down-regulate ARE-battery gene expression.
Zhang Y, Qiu L, Li S, Xiang Y, Chen J, Ren Y. Zhang Y, et al. Among authors: chen j. PLoS One. 2014 Oct 7;9(10):e109159. doi: 10.1371/journal.pone.0109159. eCollection 2014. PLoS One. 2014. PMID: 25290918 Free PMC article.
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