Wierup N - Search Results

1

Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes.

Bennet H, Balhuizen A, Medina A, Dekker Nitert M, Ottosson Laakso E, Essén S, Spégel P, Storm P, Krus U, Wierup N, Fex M. Bennet H, et al. Among authors: wierup n. Peptides. 2015 Sep;71:113-20. doi: 10.1016/j.peptides.2015.07.008. Epub 2015 Jul 20. Peptides. 2015. PMID: 26206285

2

The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas.

Wierup N, Svensson H, Mulder H, Sundler F. Wierup N, et al. Regul Pept. 2002 Jul 15;107(1-3):63-9. doi: 10.1016/s0167-0115(02)00067-8. Regul Pept. 2002. PMID: 12137967

3

The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient beta-cell mass and exocytosis.

Björkqvist M, Fex M, Renström E, Wierup N, Petersén A, Gil J, Bacos K, Popovic N, Li JY, Sundler F, Brundin P, Mulder H. Björkqvist M, et al. Among authors: wierup n. Hum Mol Genet. 2005 Mar 1;14(5):565-74. doi: 10.1093/hmg/ddi053. Epub 2005 Jan 13. Hum Mol Genet. 2005. PMID: 15649949

4

CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight.

Wierup N, Richards WG, Bannon AW, Kuhar MJ, Ahrén B, Sundler F. Wierup N, et al. Regul Pept. 2005 Jul 15;129(1-3):203-11. doi: 10.1016/j.regpep.2005.02.016. Regul Pept. 2005. PMID: 15927717 Free article.

5

CART is a novel islet regulatory peptide.

Wierup N, Sundler F. Wierup N, et al. Peptides. 2006 Aug;27(8):2031-6. doi: 10.1016/j.peptides.2006.02.011. Epub 2006 Jul 13. Peptides. 2006. PMID: 16842887 Review.

6

Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet.

Fex M, Nitert MD, Wierup N, Sundler F, Ling C, Mulder H. Fex M, et al. Among authors: wierup n. Diabetologia. 2007 Jan;50(1):74-83. doi: 10.1007/s00125-006-0464-4. Epub 2006 Nov 9. Diabetologia. 2007. PMID: 17093947

7

Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet.

Winzell MS, Brand CL, Wierup N, Sidelmann UG, Sundler F, Nishimura E, Ahrén B. Winzell MS, et al. Among authors: wierup n. Diabetologia. 2007 Jul;50(7):1453-62. doi: 10.1007/s00125-007-0675-3. Epub 2007 May 4. Diabetologia. 2007. PMID: 17479245

8

DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide.

Ahrén B, Winzell MS, Wierup N, Sundler F, Burkey B, Hughes TE. Ahrén B, et al. Among authors: wierup n. Regul Pept. 2007 Oct 4;143(1-3):97-103. doi: 10.1016/j.regpep.2007.03.008. Epub 2007 Apr 11. Regul Pept. 2007. PMID: 17482289

9

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance.

Fex M, Wierup N, Nitert MD, Ristow M, Mulder H. Fex M, et al. Among authors: wierup n. J Endocrinol. 2007 Sep;194(3):551-5. doi: 10.1677/JOE-07-0161. J Endocrinol. 2007. PMID: 17761894

10

A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis.

Fex M, Haemmerle G, Wierup N, Dekker-Nitert M, Rehn M, Ristow M, Zechner R, Sundler F, Holm C, Eliasson L, Mulder H. Fex M, et al. Among authors: wierup n. Diabetologia. 2009 Feb;52(2):271-80. doi: 10.1007/s00125-008-1191-9. Epub 2008 Nov 21. Diabetologia. 2009. PMID: 19023560

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