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Page 1
Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
Lamoral-Theys D, Andolfi A, Van Goietsenoven G, Cimmino A, Le Calvé B, Wauthoz N, Mégalizzi V, Gras T, Bruyère C, Dubois J, Mathieu V, Kornienko A, Kiss R, Evidente A. Lamoral-Theys D, et al. Among authors: mathieu v. J Med Chem. 2009 Oct 22;52(20):6244-56. doi: 10.1021/jm901031h. J Med Chem. 2009. PMID: 19788245 Free PMC article.
Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas.
Van Goietsenoven G, Hutton J, Becker JP, Lallemand B, Robert F, Lefranc F, Pirker C, Vandenbussche G, Van Antwerpen P, Evidente A, Berger W, Prévost M, Pelletier J, Kiss R, Kinzy TG, Kornienko A, Mathieu V. Van Goietsenoven G, et al. Among authors: mathieu v. FASEB J. 2010 Nov;24(11):4575-84. doi: 10.1096/fj.10-162263. Epub 2010 Jul 19. FASEB J. 2010. PMID: 20643906 Free PMC article.
In vitro anticancer activity, toxicity and structure-activity relationships of phyllostictine A, a natural oxazatricycloalkenone produced by the fungus Phyllosticta cirsii.
Le Calvé B, Lallemand B, Perrone C, Lenglet G, Depauw S, Van Goietsenoven G, Bury M, Vurro M, Herphelin F, Andolfi A, Zonno MC, Mathieu V, Dufrasne F, Van Antwerpen P, Poumay Y, David-Cordonnier MH, Evidente A, Kiss R. Le Calvé B, et al. Among authors: mathieu v. Toxicol Appl Pharmacol. 2011 Jul 1;254(1):8-17. doi: 10.1016/j.taap.2011.03.027. Epub 2011 Apr 12. Toxicol Appl Pharmacol. 2011. PMID: 21504755
Trivanillic polyphenols with anticancer cytostatic effects through the targeting of multiple kinases and intracellular Ca2+ release.
Lamoral-Theys D, Wauthoz N, Heffeter P, Mathieu V, Jungwirth U, Lefranc F, Nève J, Dubois J, Dufrasne F, Amighi K, Berger W, Gailly P, Kiss R. Lamoral-Theys D, et al. Among authors: mathieu v. J Cell Mol Med. 2012 Jul;16(7):1421-34. doi: 10.1111/j.1582-4934.2011.01403.x. J Cell Mol Med. 2012. PMID: 21810170 Free PMC article.
N-(2-{3-[3,5-bis(trifluoromethyl)phenyl]ureido}ethyl)-glycyrrhetinamide (6b): a novel anticancer glycyrrhetinic acid derivative that targets the proteasome and displays anti-kinase activity.
Lallemand B, Chaix F, Bury M, Bruyère C, Ghostin J, Becker JP, Delporte C, Gelbcke M, Mathieu V, Dubois J, Prévost M, Jabin I, Kiss R. Lallemand B, et al. Among authors: mathieu v. J Med Chem. 2011 Oct 13;54(19):6501-13. doi: 10.1021/jm200285z. Epub 2011 Sep 2. J Med Chem. 2011. PMID: 21888390
4-Bromo-2-(piperidin-1-yl)thiazol-5-yl-phenyl methanone (12b) inhibits Na+/K(+)-ATPase and Ras oncogene activity in cancer cells.
Lefranc F, Xu Z, Burth P, Mathieu V, Revelant G, de Castro Faria MV, Noyon C, Garcia DG, Dufour D, Bruyère C, Gonçalves-de-Albuquerque CF, Van Antwerpen P, Rogister B, Hesse S, Kirsch G, Kiss R. Lefranc F, et al. Among authors: mathieu v. Eur J Med Chem. 2013 May;63:213-23. doi: 10.1016/j.ejmech.2013.01.046. Epub 2013 Feb 16. Eur J Med Chem. 2013. PMID: 23474907
163 results