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CD34-Selected Hematopoietic Stem Cell Transplants Conditioned with Myeloablative Regimens and Antithymocyte Globulin for Advanced Myelodysplastic Syndrome: Limited Graft-versus-Host Disease without Increased Relapse.
Tamari R, Chung SS, Papadopoulos EB, Jakubowski AA, Hilden P, Devlin SM, Goldberg JD, Perales MA, Ponce DM, Sauter CS, Maloy MA, Herman DY, Klimek V, Young JW, O'Reilly RJ, Giralt SA, Castro-Malaspina H. Tamari R, et al. Among authors: klimek v. Biol Blood Marrow Transplant. 2015 Dec;21(12):2106-2114. doi: 10.1016/j.bbmt.2015.07.010. Epub 2015 Jul 14. Biol Blood Marrow Transplant. 2015. PMID: 26187863 Free PMC article.
Hematopoietic stem cell mobilization with intravenous melphalan and G-CSF in patients with chemoresponsive multiple myeloma: report of a phase II trial.
Gupta S, Zhou P, Hassoun H, Kewalramani T, Reich L, Costello S, Drake L, Klimek V, Dhodapkar M, Teruya-Feldstein J, Hedvat C, Kalakonda N, Fleisher M, Filippa D, Qin J, Nimer SD, Comenzo RL. Gupta S, et al. Among authors: klimek v. Bone Marrow Transplant. 2005 Mar;35(5):441-7. doi: 10.1038/sj.bmt.1704779. Bone Marrow Transplant. 2005. PMID: 15640822 Clinical Trial.
High-dose melphalan and auto-SCT in patients with monoclonal Ig deposition disease.
Hassoun H, Flombaum C, D'Agati VD, Rafferty BT, Cohen A, Klimek VM, Boruchov A, Kewalramani T, Reich L, Nimer SD, Comenzo RL. Hassoun H, et al. Among authors: klimek vm. Bone Marrow Transplant. 2008 Sep;42(6):405-12. doi: 10.1038/bmt.2008.179. Epub 2008 Jun 23. Bone Marrow Transplant. 2008. PMID: 18574442
MSI2 is required for maintaining activated myelodysplastic syndrome stem cells.
Taggart J, Ho TC, Amin E, Xu H, Barlowe TS, Perez AR, Durham BH, Tivnan P, Okabe R, Chow A, Vu L, Park SM, Prieto C, Famulare C, Patel M, Lengner CJ, Verma A, Roboz G, Guzman M, Klimek VM, Abdel-Wahab O, Leslie C, Nimer SD, Kharas MG. Taggart J, et al. Nat Commun. 2016 Feb 22;7:10739. doi: 10.1038/ncomms10739. Nat Commun. 2016. PMID: 26898884 Free PMC article.
Mutational correlates of response to hypomethylating agent therapy in acute myeloid leukemia.
Coombs CC, Sallman DA, Devlin SM, Dixit S, Mohanty A, Knapp K, Al Ali NH, Lancet JE, List AF, Komrokji RS, Padron E, Arcila ME, Klimek VM, van den Brink MR, Tallman MS, Levine RL, Rampal RK, Rapaport F. Coombs CC, et al. Haematologica. 2016 Nov;101(11):e457-e460. doi: 10.3324/haematol.2016.148999. Epub 2016 Jul 14. Haematologica. 2016. PMID: 27418649 Free PMC article. No abstract available.
CD99 is a therapeutic target on disease stem cells in myeloid malignancies.
Chung SS, Eng WS, Hu W, Khalaj M, Garrett-Bakelman FE, Tavakkoli M, Levine RL, Carroll M, Klimek VM, Melnick AM, Park CY. Chung SS, et al. Sci Transl Med. 2017 Jan 25;9(374):eaaj2025. doi: 10.1126/scitranslmed.aaj2025. Sci Transl Med. 2017. PMID: 28123069 Free PMC article.
Allogeneic Hematopoietic Stem Cell Transplantation Is Underutilized in Older Patients with Myelodysplastic Syndromes.
Getta BM, Kishtagari A, Hilden P, Tallman MS, Maloy M, Gonzales P, Castro-Malaspina H, Perales MA, Giralt S, Tamari R, Klimek V. Getta BM, et al. Among authors: klimek v. Biol Blood Marrow Transplant. 2017 Jul;23(7):1078-1086. doi: 10.1016/j.bbmt.2017.03.020. Epub 2017 Mar 20. Biol Blood Marrow Transplant. 2017. PMID: 28336325 Free PMC article.
Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML.
Yoshimi A, Balasis ME, Vedder A, Feldman K, Ma Y, Zhang H, Lee SC, Letson C, Niyongere S, Lu SX, Ball M, Taylor J, Zhang Q, Zhao Y, Youssef S, Chung YR, Zhang XJ, Durham BH, Yang W, List AF, Loh ML, Klimek V, Berger MF, Stieglitz E, Padron E, Abdel-Wahab O. Yoshimi A, et al. Among authors: klimek v. Blood. 2017 Jul 27;130(4):397-407. doi: 10.1182/blood-2017-01-763219. Epub 2017 Jun 2. Blood. 2017. PMID: 28576879 Free PMC article.
137 results