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SNAP23 is selectively expressed in airway secretory cells and mediates baseline and stimulated mucin secretion.
Ren B, Azzegagh Z, Jaramillo AM, Zhu Y, Pardo-Saganta A, Bagirzadeh R, Flores JR, Han W, Tang YJ, Tu J, Alanis DM, Evans CM, Guindani M, Roche PA, Rajagopal J, Chen J, Davis CW, Tuvim MJ, Dickey BF. Ren B, et al. Among authors: bagirzadeh r. Biosci Rep. 2015 Apr 28;35(3):e00220. doi: 10.1042/BSR20150004. Biosci Rep. 2015. PMID: 26182382 Free PMC article.
Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells.
Kim K, Petrova YM, Scott BL, Nigam R, Agrawal A, Evans CM, Azzegagh Z, Gomez A, Rodarte EM, Olkkonen VM, Bagirzadeh R, Piccotti L, Ren B, Yoon JH, McNew JA, Adachi R, Tuvim MJ, Dickey BF. Kim K, et al. Among authors: bagirzadeh r. Biochem J. 2012 Sep 15;446(3):383-94. doi: 10.1042/BJ20120057. Biochem J. 2012. PMID: 22694344 Free PMC article.
Intrinsic GATA4 expression sensitizes the aortic root to dilation in a Loeys-Dietz syndrome mouse model.
Bramel EE, Espinoza Camejo WA, Creamer TJ, Restrepo L, Saqib M, Bagirzadeh R, Zeng A, Mitchell JT, Stein-O'Brien GL, Pedroza AJ, Fischbein MP, Dietz HC, Gallo MacFarlane E. Bramel EE, et al. Among authors: bagirzadeh r. Nat Cardiovasc Res. 2024 Dec;3(12):1468-1481. doi: 10.1038/s44161-024-00562-5. Epub 2024 Nov 20. Nat Cardiovasc Res. 2024. PMID: 39567770 Free PMC article.
Genetic Code Expansion History and Modern Innovations.
Costello A, Peterson AA, Chen PH, Bagirzadeh R, Lanster DL, Badran AH. Costello A, et al. Among authors: bagirzadeh r. Chem Rev. 2024 Nov 13;124(21):11962-12005. doi: 10.1021/acs.chemrev.4c00275. Epub 2024 Oct 28. Chem Rev. 2024. PMID: 39466033 Review.
Intrinsic Gata4 expression sensitizes the aortic root to dilation in a Loeys-Dietz syndrome mouse model.
Bramel EE, Camejo WAE, Creamer TJ, Restrepo L, Saqib M, Bagirzadeh R, Zeng A, Mitchell JT, Stein-O'Brien GL, Pedroza AJ, Fischbein MP, Dietz HC, MacFarlane EG. Bramel EE, et al. Among authors: bagirzadeh r. Res Sq [Preprint]. 2024 Jun 5:rs.3.rs-4420617. doi: 10.21203/rs.3.rs-4420617/v1. Res Sq. 2024. Update in: Nat Cardiovasc Res. 2024 Dec;3(12):1468-1481. doi: 10.1038/s44161-024-00562-5 PMID: 38883722 Free PMC article. Updated. Preprint.
Distinct Contribution of Global and Regional Angiotensin II Type 1a Receptor Inactivation to Amelioration of Aortopathy in Tgfbr1 M318R/+ Mice.
Bramel EE, Bagirzadeh R, Saqib M, Creamer TJ, Espinoza Camejo WA, Roker LA, Pardo Habashi J, Dietz HC, Gallo MacFarlane E. Bramel EE, et al. Among authors: bagirzadeh r. Front Cardiovasc Med. 2022 Jun 22;9:936142. doi: 10.3389/fcvm.2022.936142. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35811726 Free PMC article.
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis.
Shin JY, Beckett JD, Bagirzadeh R, Creamer TJ, Shah AA, McMahan Z, Paik JJ, Sampedro MM, MacFarlane EG, Beer MA, Warren D, Wigley FM, Dietz HC. Shin JY, et al. Among authors: bagirzadeh r. Sci Transl Med. 2019 Jun 19;11(497):eaaw0790. doi: 10.1126/scitranslmed.aaw0790. Sci Transl Med. 2019. PMID: 31217334 Free PMC article.
Lineage-specific events underlie aortic root aneurysm pathogenesis in Loeys-Dietz syndrome.
MacFarlane EG, Parker SJ, Shin JY, Kang BE, Ziegler SG, Creamer TJ, Bagirzadeh R, Bedja D, Chen Y, Calderon JF, Weissler K, Frischmeyer-Guerrerio PA, Lindsay ME, Habashi JP, Dietz HC. MacFarlane EG, et al. Among authors: bagirzadeh r. J Clin Invest. 2019 Feb 1;129(2):659-675. doi: 10.1172/JCI123547. Epub 2019 Jan 7. J Clin Invest. 2019. PMID: 30614814 Free PMC article.
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