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Page 1
Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion.
Tervonen TA, Belitškin D, Pant SM, Englund JI, Marques E, Ala-Hongisto H, Nevalaita L, Sihto H, Heikkilä P, Leidenius M, Hewitson K, Ramachandra M, Moilanen A, Joensuu H, Kovanen PE, Poso A, Klefström J. Tervonen TA, et al. Among authors: poso a. Oncogene. 2016 Apr 7;35(14):1832-46. doi: 10.1038/onc.2015.248. Epub 2015 Jul 13. Oncogene. 2016. PMID: 26165838
Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na.
Mäki-Jouppila JH, Laine LJ, Rehnberg J, Narvi E, Tiikkainen P, Hukasova E, Halonen P, Lindqvist A, Kallio L, Poso A, Kallio MJ. Mäki-Jouppila JH, et al. Among authors: poso a. Mol Cancer Ther. 2014 May;13(5):1054-66. doi: 10.1158/1535-7163.MCT-13-0685. Epub 2014 Apr 18. Mol Cancer Ther. 2014. PMID: 24748653
1,3,4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity determinants by molecular modelling.
Käsnänen H, Minkkilä A, Taupila S, Patel JZ, Parkkari T, Lahtela-Kakkonen M, Saario SM, Nevalainen T, Poso A. Käsnänen H, et al. Among authors: poso a. Eur J Pharm Sci. 2013 Jun 14;49(3):423-33. doi: 10.1016/j.ejps.2013.03.015. Epub 2013 Apr 2. Eur J Pharm Sci. 2013. PMID: 23557840
Identification of novel CYP2A6 inhibitors by virtual screening.
Rahnasto MK, Raunio HA, Wittekindt C, Salminen KA, Leppänen J, Juvonen RO, Poso A, Lahtela-Kakkonen MK. Rahnasto MK, et al. Among authors: poso a. Bioorg Med Chem. 2011 Dec 1;19(23):7186-93. doi: 10.1016/j.bmc.2011.09.054. Epub 2011 Oct 4. Bioorg Med Chem. 2011. PMID: 22019468
303 results