Danilov AV - Search Results

1

Targeting neddylation induces DNA damage and checkpoint activation and sensitizes chronic lymphocytic leukemia B cells to alkylating agents.

Paiva C, Godbersen JC, Berger A, Brown JR, Danilov AV. Paiva C, et al. Among authors: danilov av. Cell Death Dis. 2015 Jul 9;6(7):e1807. doi: 10.1038/cddis.2015.161. Cell Death Dis. 2015. PMID: 26158513 Free PMC article.

2

Dipeptidyl peptidase 2 apoptosis assay determines the B-cell activation stage and predicts prognosis in chronic lymphocytic leukemia.

Danilov AV, Danilova OV, Brown JR, Rabinowitz A, Klein AK, Huber BT. Danilov AV, et al. Exp Hematol. 2010 Dec;38(12):1167-77. doi: 10.1016/j.exphem.2010.08.008. Epub 2010 Sep 24. Exp Hematol. 2010. PMID: 20817072 Free PMC article.

3

Vinblastine rapidly induces NOXA and acutely sensitizes primary chronic lymphocytic leukemia cells to ABT-737.

Bates DJ, Danilov AV, Lowrey CH, Eastman A. Bates DJ, et al. Among authors: danilov av. Mol Cancer Ther. 2013 Aug;12(8):1504-14. doi: 10.1158/1535-7163.MCT-12-1197. Epub 2013 May 30. Mol Cancer Ther. 2013. PMID: 23723123 Free PMC article.

4

Toward a cure for chronic lymphocytic leukemia: an attack on multiple fronts.

Danilov AV, Soderquist RS, Bates DJ, Eastman A. Danilov AV, et al. Expert Rev Anticancer Ther. 2013 Sep;13(9):1009-12. doi: 10.1586/14737140.2013.825424. Expert Rev Anticancer Ther. 2013. PMID: 24053199 Free PMC article. No abstract available.

5

The putative BH3 mimetic S1 sensitizes leukemia to ABT-737 by increasing reactive oxygen species, inducing endoplasmic reticulum stress, and upregulating the BH3-only protein NOXA.

Soderquist R, Pletnev AA, Danilov AV, Eastman A. Soderquist R, et al. Among authors: danilov av. Apoptosis. 2014 Jan;19(1):201-9. doi: 10.1007/s10495-013-0910-y. Apoptosis. 2014. PMID: 24072590 Free PMC article.

6

Pro-apoptotic TP53 homolog TAp63 is repressed via epigenetic silencing and B-cell receptor signalling in chronic lymphocytic leukaemia.

Humphries LA, Godbersen JC, Danilova OV, Kaur P, Christensen BC, Danilov AV. Humphries LA, et al. Among authors: danilov av. Br J Haematol. 2013 Dec;163(5):590-602. doi: 10.1111/bjh.12580. Epub 2013 Sep 30. Br J Haematol. 2013. PMID: 24117128 Free PMC article.

7

The Nedd8-activating enzyme inhibitor MLN4924 thwarts microenvironment-driven NF-κB activation and induces apoptosis in chronic lymphocytic leukemia B cells.

Godbersen JC, Humphries LA, Danilova OV, Kebbekus PE, Brown JR, Eastman A, Danilov AV. Godbersen JC, et al. Among authors: danilov av. Clin Cancer Res. 2014 Mar 15;20(6):1576-89. doi: 10.1158/1078-0432.CCR-13-0987. Clin Cancer Res. 2014. PMID: 24634471 Free PMC article.

8

A new hope: novel therapeutic approaches to treatment of chronic lymphocytic leukaemia with defects in TP53.

Shindiapina P, Brown JR, Danilov AV. Shindiapina P, et al. Among authors: danilov av. Br J Haematol. 2014 Oct;167(2):149-61. doi: 10.1111/bjh.13042. Epub 2014 Jul 21. Br J Haematol. 2014. PMID: 25040077 Free article. Review.

9

MIR21 is differentially expressed in the lymphoid tissue and modulated by stromal signalling in chronic lymphocytic leukaemia.

Danilova OV, Paiva C, Kaur P, Kamal A, Sempere LF, Danilov AV. Danilova OV, et al. Among authors: danilov av. Br J Haematol. 2015 Jul;170(2):272-5. doi: 10.1111/bjh.13282. Epub 2015 Jan 29. Br J Haematol. 2015. PMID: 25643738 Free article. No abstract available.

10

Targeting neddylation effectively antagonizes nuclear factor-κB in chronic lymphocytic leukemia B-cells.

Godbersen JC, Paiva C, Danilova OV, Berger A, Brown JR, Danilov AV. Godbersen JC, et al. Among authors: danilov av. Leuk Lymphoma. 2015 May;56(5):1566-9. doi: 10.3109/10428194.2014.990901. Leuk Lymphoma. 2015. PMID: 26086969

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