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Efficacy of PD-1 blockade in cervical cancer is related to a CD8+FoxP3+CD25+ T-cell subset with operational effector functions despite high immune checkpoint levels.
Heeren AM, Rotman J, Stam AGM, Pocorni N, Gassama AA, Samuels S, Bleeker MCG, Mom CH, Zijlmans HJMAA, Kenter GG, Jordanova ES, de Gruijl TD. Heeren AM, et al. J Immunother Cancer. 2019 Feb 12;7(1):43. doi: 10.1186/s40425-019-0526-z. J Immunother Cancer. 2019. PMID: 30755279 Free PMC article.
High-efficiency lysis of cervical cancer by allogeneic NK cells derived from umbilical cord progenitors is independent of HLA status.
Veluchamy JP, Heeren AM, Spanholtz J, van Eendenburg JD, Heideman DA, Kenter GG, Verheul HM, van der Vliet HJ, Jordanova ES, de Gruijl TD. Veluchamy JP, et al. Among authors: heeren am. Cancer Immunol Immunother. 2017 Jan;66(1):51-61. doi: 10.1007/s00262-016-1919-1. Epub 2016 Oct 25. Cancer Immunol Immunother. 2017. PMID: 27783105 Free PMC article.
Unlocking the therapeutic potential of primary tumor-draining lymph nodes.
Rotman J, Koster BD, Jordanova ES, Heeren AM, de Gruijl TD. Rotman J, et al. Among authors: heeren am. Cancer Immunol Immunother. 2019 Oct;68(10):1681-1688. doi: 10.1007/s00262-019-02330-y. Epub 2019 Apr 3. Cancer Immunol Immunother. 2019. PMID: 30944963 Free PMC article. Review.
19 results