Wang N - Search Results

1

Palladium(II)-Catalyzed C-H Bond Activation/C-C Coupling/Intramolecular Tsuji-Trost Reaction Cascade: Facile Access to 2H-Pyranonaphthoquinones.

Bian J, Qian X, Wang N, Mu T, Li X, Sun H, Zhang L, You Q, Zhang X. Bian J, et al. Among authors: wang n. Org Lett. 2015 Jul 17;17(14):3410-3. doi: 10.1021/acs.orglett.5b01304. Epub 2015 Jul 7. Org Lett. 2015. PMID: 26151353

2

2-Substituted 3-methylnaphtho[1,2-b]furan-4,5-diones as novel L-shaped ortho-quinone substrates for NAD(P)H:quinone oxidoreductase (NQO1).

Bian J, Deng B, Xu L, Xu X, Wang N, Hu T, Yao Z, Du J, Yang L, Lei Y, Li X, Sun H, Zhang X, You Q. Bian J, et al. Among authors: wang n. Eur J Med Chem. 2014 Jul 23;82:56-67. doi: 10.1016/j.ejmech.2014.05.041. Epub 2014 May 14. Eur J Med Chem. 2014. PMID: 24874653

3

Novel naphtho[2,1-d]oxazole-4,5-diones as NQO1 substrates with improved aqueous solubility: Design, synthesis, and in vivo antitumor evaluation.

Li X, Bian J, Wang N, Qian X, Gu J, Mu T, Fan J, Yang X, Li S, Yang T, Sun H, You Q, Zhang X. Li X, et al. Among authors: wang n. Bioorg Med Chem. 2016 Mar 1;24(5):1006-13. doi: 10.1016/j.bmc.2016.01.024. Epub 2016 Jan 16. Bioorg Med Chem. 2016. PMID: 26803578

4

Affinity-based small fluorescent probe for NAD(P)H:quinone oxidoreductase 1 (NQO1). Design, synthesis and pharmacological evaluation.

Bian J, Li X, Xu L, Wang N, Qian X, You Q, Zhang X. Bian J, et al. Among authors: wang n. Eur J Med Chem. 2017 Feb 15;127:828-839. doi: 10.1016/j.ejmech.2016.10.062. Epub 2016 Nov 1. Eur J Med Chem. 2017. PMID: 27829520

5

Discovery of quinone-directed antitumor agents selectively bioactivated by NQO1 over CPR with improved safety profile.

Bian J, Li X, Wang N, Wu X, You Q, Zhang X. Bian J, et al. Among authors: wang n. Eur J Med Chem. 2017 Mar 31;129:27-40. doi: 10.1016/j.ejmech.2017.02.004. Epub 2017 Feb 6. Eur J Med Chem. 2017. PMID: 28214631

6

Current Development of ROS-Modulating Agents as Novel Antitumor Therapy.

Wang N, Wu Y, Bian J, Qian X, Lin H, Sun H, You Q, Zhang X. Wang N, et al. Curr Cancer Drug Targets. 2017;17(2):122-136. doi: 10.2174/1568009616666160216125833. Curr Cancer Drug Targets. 2017. PMID: 26881931 Review.

7

Application of cation-π interactions in enzyme-substrate binding: Design, synthesis, biological evaluation, and molecular dynamics insights of novel hydrophilic substrates for NQO1.

Gong Q, Yu Q, Wang N, Hu J, Wang P, Yang F, Li T, You Q, Li X, Zhang X. Gong Q, et al. Among authors: wang p, wang n. Eur J Med Chem. 2021 Oct 5;221:113515. doi: 10.1016/j.ejmech.2021.113515. Epub 2021 May 6. Eur J Med Chem. 2021. PMID: 33984806

8

Hydrogen Peroxide Inducible JAK3 Covalent Inhibitor: Prodrug for the Treatment of RA with Enhanced Safety Profile.

Bao Q, Zhang L, Wang N, Gabet B, Yang W, Gao X, You Q, Jiang Z. Bao Q, et al. Among authors: wang n. ACS Med Chem Lett. 2020 Oct 5;11(11):2182-2189. doi: 10.1021/acsmedchemlett.0c00323. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214827 Free PMC article.

9

Identification of New Potent Human Uncoupling Protein 1 (UCP1) Agonists Using Virtual Screening and in vitro Approaches.

Lu HY, Wang N, Li X, Huang Y, Wang J, Zhao QC. Lu HY, et al. Among authors: wang j, wang n. Mol Inform. 2019 Oct;38(10):e1900030. doi: 10.1002/minf.201900030. Epub 2019 Jul 2. Mol Inform. 2019. PMID: 31264791

10

ZW290 Increases Cold Tolerance by Inducing Thermogenesis via the Upregulation of Uncoupling Protein 1 in Brown Adipose Tissue In Vitro and In Vivo.

Wang N, Lu HY, Li X, Du YJ, Meng WH, Ding HW, Zhao QC. Wang N, et al. Lipids. 2019 May;54(5):265-276. doi: 10.1002/lipd.12148. Lipids. 2019. PMID: 31087415

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