Iyer SP - Search Results

1

HEXIM1 induction is mechanistically involved in mediating anti-AML activity of BET protein bromodomain antagonist.

Devaraj SG, Fiskus W, Shah B, Qi J, Sun B, Iyer SP, Sharma S, Bradner JE, Bhalla KN. Devaraj SG, et al. Among authors: iyer sp. Leukemia. 2016 Feb;30(2):504-8. doi: 10.1038/leu.2015.142. Epub 2015 Jun 15. Leukemia. 2016. PMID: 26148704 Free PMC article. No abstract available.

2

WTAP is a novel oncogenic protein in acute myeloid leukemia.

Bansal H, Yihua Q, Iyer SP, Ganapathy S, Proia DA, Penalva LO, Uren PJ, Suresh U, Carew JS, Karnad AB, Weitman S, Tomlinson GE, Rao MK, Kornblau SM, Bansal S. Bansal H, et al. Among authors: iyer sp. Leukemia. 2014 May;28(5):1171-4. doi: 10.1038/leu.2014.16. Epub 2014 Jan 13. Leukemia. 2014. PMID: 24413322 Free PMC article. No abstract available.

3

Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells.

Fiskus W, Sharma S, Qi J, Valenta JA, Schaub LJ, Shah B, Peth K, Portier BP, Rodriguez M, Devaraj SG, Zhan M, Sheng J, Iyer SP, Bradner JE, Bhalla KN. Fiskus W, et al. Among authors: iyer sp. Mol Cancer Ther. 2014 May;13(5):1142-54. doi: 10.1158/1535-7163.MCT-13-0770. Epub 2014 Jan 16. Mol Cancer Ther. 2014. PMID: 24435446

4

Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells.

Fiskus W, Sharma S, Shah B, Portier BP, Devaraj SG, Liu K, Iyer SP, Bearss D, Bhalla KN. Fiskus W, et al. Among authors: iyer sp. Leukemia. 2014 Nov;28(11):2155-64. doi: 10.1038/leu.2014.119. Epub 2014 Apr 4. Leukemia. 2014. PMID: 24699304 Free PMC article.

5

BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD.

Fiskus W, Sharma S, Qi J, Shah B, Devaraj SG, Leveque C, Portier BP, Iyer S, Bradner JE, Bhalla KN. Fiskus W, et al. Mol Cancer Ther. 2014 Oct;13(10):2315-27. doi: 10.1158/1535-7163.MCT-14-0258. Epub 2014 Jul 22. Mol Cancer Ther. 2014. PMID: 25053825 Free PMC article.

6

Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells.

Fiskus W, Sharma S, Saha S, Shah B, Devaraj SG, Sun B, Horrigan S, Leveque C, Zu Y, Iyer S, Bhalla KN. Fiskus W, et al. Leukemia. 2015 Jun;29(6):1267-78. doi: 10.1038/leu.2014.340. Epub 2014 Dec 8. Leukemia. 2015. PMID: 25482131 Free PMC article.

7

Oligonucleotide aptamer-drug conjugates for targeted therapy of acute myeloid leukemia.

Zhao N, Pei SN, Qi J, Zeng Z, Iyer SP, Lin P, Tung CH, Zu Y. Zhao N, et al. Among authors: iyer sp. Biomaterials. 2015 Oct;67:42-51. doi: 10.1016/j.biomaterials.2015.07.025. Epub 2015 Jul 15. Biomaterials. 2015. PMID: 26204224 Free PMC article.

8

A unique aptamer-drug conjugate for targeted therapy of multiple myeloma.

Wen J, Tao W, Hao S, Iyer SP, Zu Y. Wen J, et al. Among authors: iyer sp. Leukemia. 2016 Apr;30(4):987-91. doi: 10.1038/leu.2015.216. Epub 2015 Aug 5. Leukemia. 2016. PMID: 26242462 No abstract available.

9

Leukapheresis reduces 4-week mortality in acute myeloid leukemia patients with hyperleukocytosis - a retrospective study from a tertiary center.

Nan X, Qin Q, Gentille C, Ensor J, Leveque C, Pingali SR, Phan AT, Rice L, Iyer S. Nan X, et al. Leuk Lymphoma. 2017 Sep;58(9):1-11. doi: 10.1080/10428194.2016.1277386. Epub 2017 Jan 31. Leuk Lymphoma. 2017. PMID: 28140714

10

Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells.

Fiskus W, Sharma S, Shah B, Portier BP, Devaraj SGT, Liu K, Iyer SP, Bearss D, Bhalla KN. Fiskus W, et al. Among authors: iyer sp. Leukemia. 2017 Jul;31(7):1658. doi: 10.1038/leu.2017.77. Epub 2017 Mar 21. Leukemia. 2017. PMID: 28322226

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