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Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.
Veazey RS, Klasse PJ, Ketas TJ, Reeves JD, Piatak M Jr, Kunstman K, Kuhmann SE, Marx PA, Lifson JD, Dufour J, Mefford M, Pandrea I, Wolinsky SM, Doms RW, DeMartino JA, Siciliano SJ, Lyons K, Springer MS, Moore JP. Veazey RS, et al. Among authors: dufour j. J Exp Med. 2003 Nov 17;198(10):1551-62. doi: 10.1084/jem.20031266. J Exp Med. 2003. PMID: 14623909 Free PMC article.
Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts.
Pandrea I, Apetrei C, Dufour J, Dillon N, Barbercheck J, Metzger M, Jacquelin B, Bohm R, Marx PA, Barre-Sinoussi F, Hirsch VM, Müller-Trutwin MC, Lackner AA, Veazey RS. Pandrea I, et al. Among authors: dufour j. J Virol. 2006 May;80(10):4858-67. doi: 10.1128/JVI.80.10.4858-4867.2006. J Virol. 2006. PMID: 16641277 Free PMC article.
Paucity of CD4+CCR5+ T cells is a typical feature of natural SIV hosts.
Pandrea I, Apetrei C, Gordon S, Barbercheck J, Dufour J, Bohm R, Sumpter B, Roques P, Marx PA, Hirsch VM, Kaur A, Lackner AA, Veazey RS, Silvestri G. Pandrea I, et al. Among authors: dufour j. Blood. 2007 Feb 1;109(3):1069-76. doi: 10.1182/blood-2006-05-024364. Epub 2006 Sep 26. Blood. 2007. PMID: 17003371 Free PMC article.
903 results