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Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo.
Soccio RE, Chen ER, Rajapurkar SR, Safabakhsh P, Marinis JM, Dispirito JR, Emmett MJ, Briggs ER, Fang B, Everett LJ, Lim HW, Won KJ, Steger DJ, Wu Y, Civelek M, Voight BF, Lazar MA. Soccio RE, et al. Among authors: briggs er. Cell. 2015 Jul 2;162(1):33-44. doi: 10.1016/j.cell.2015.06.025. Cell. 2015. PMID: 26140591 Free PMC article.
The nuclear receptor Rev-erbα controls circadian thermogenic plasticity.
Gerhart-Hines Z, Feng D, Emmett MJ, Everett LJ, Loro E, Briggs ER, Bugge A, Hou C, Ferrara C, Seale P, Pryma DA, Khurana TS, Lazar MA. Gerhart-Hines Z, et al. Among authors: briggs er. Nature. 2013 Nov 21;503(7476):410-413. doi: 10.1038/nature12642. Epub 2013 Oct 27. Nature. 2013. PMID: 24162845 Free PMC article.
Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice.
Soccio RE, Li Z, Chen ER, Foong YH, Benson KK, Dispirito JR, Mullican SE, Emmett MJ, Briggs ER, Peed LC, Dzeng RK, Medina CJ, Jolivert JF, Kissig M, Rajapurkar SR, Damle M, Lim HW, Won KJ, Seale P, Steger DJ, Lazar MA. Soccio RE, et al. Among authors: briggs er. J Clin Invest. 2017 Apr 3;127(4):1451-1462. doi: 10.1172/JCI91211. Epub 2017 Feb 27. J Clin Invest. 2017. PMID: 28240605 Free PMC article.
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge.
Emmett MJ, Lim HW, Jager J, Richter HJ, Adlanmerini M, Peed LC, Briggs ER, Steger DJ, Ma T, Sims CA, Baur JA, Pei L, Won KJ, Seale P, Gerhart-Hines Z, Lazar MA. Emmett MJ, et al. Among authors: briggs er. Nature. 2017 Jun 22;546(7659):544-548. doi: 10.1038/nature22819. Epub 2017 Jun 14. Nature. 2017. PMID: 28614293 Free PMC article.
17 results