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Page 1
Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor.
Hirano K, Chen WS, Chueng AL, Dunne AA, Seredenina T, Filippova A, Ramachandran S, Bridges A, Chaudry L, Pettman G, Allan C, Duncan S, Lee KC, Lim J, Ma MT, Ong AB, Ye NY, Nasir S, Mulyanidewi S, Aw CC, Oon PP, Liao S, Li D, Johns DG, Miller ND, Davies CH, Browne ER, Matsuoka Y, Chen DW, Jaquet V, Rutter AR. Hirano K, et al. Among authors: rutter ar. Antioxid Redox Signal. 2015 Aug 10;23(5):358-74. doi: 10.1089/ars.2014.6202. Antioxid Redox Signal. 2015. PMID: 26135714 Free PMC article.
Response to Pick.
Jaquet V, Rutter AR. Jaquet V, et al. Among authors: rutter ar. Antioxid Redox Signal. 2015 Nov 20;23(15):1251-3. doi: 10.1089/ars.2015.6565. Antioxid Redox Signal. 2015. PMID: 26566578
GSK356278, a potent, selective, brain-penetrant phosphodiesterase 4 inhibitor that demonstrates anxiolytic and cognition-enhancing effects without inducing side effects in preclinical species.
Rutter AR, Poffe A, Cavallini P, Davis TG, Schneck J, Negri M, Vicentini E, Montanari D, Arban R, Gray FA, Davies CH, Wren PB. Rutter AR, et al. J Pharmacol Exp Ther. 2014 Jul;350(1):153-63. doi: 10.1124/jpet.114.214155. Epub 2014 Apr 30. J Pharmacol Exp Ther. 2014. PMID: 24784567
Probing Mitochondrial Permeability Transition Pore Activity in Nucleated Cells and Platelets by High-Throughput Screening Assays Suggests Involvement of Protein Phosphatase 2B in Mitochondrial Dynamics.
Chen MX, Ward E, Caivano M, Toh S, Searle K, Ramachandran S, Lacroix Y, Ahmed M, Rutter AR. Chen MX, et al. Among authors: rutter ar. Assay Drug Dev Technol. 2018 Dec;16(8):445-455. doi: 10.1089/adt.2018.872. Epub 2018 Nov 27. Assay Drug Dev Technol. 2018. PMID: 30481043
Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.
Reynolds DS, Rosahl TW, Cirone J, O'Meara GF, Haythornthwaite A, Newman RJ, Myers J, Sur C, Howell O, Rutter AR, Atack J, Macaulay AJ, Hadingham KL, Hutson PH, Belelli D, Lambert JJ, Dawson GR, McKernan R, Whiting PJ, Wafford KA. Reynolds DS, et al. Among authors: rutter ar. J Neurosci. 2003 Sep 17;23(24):8608-17. doi: 10.1523/JNEUROSCI.23-24-08608.2003. J Neurosci. 2003. PMID: 13679430 Free PMC article.
17 results