Rozhok AI - Search Results

1

A Critical Examination of the "Bad Luck" Explanation of Cancer Risk.

Rozhok AI, Wahl GM, DeGregori J. Rozhok AI, et al. Cancer Prev Res (Phila). 2015 Sep;8(9):762-4. doi: 10.1158/1940-6207.CAPR-15-0229. Epub 2015 Jun 29. Cancer Prev Res (Phila). 2015. PMID: 26122457 Free PMC article.

2

Stochastic modeling indicates that aging and somatic evolution in the hematopoetic system are driven by non-cell-autonomous processes.

Rozhok AI, Salstrom JL, DeGregori J. Rozhok AI, et al. Aging (Albany NY). 2014 Dec;6(12):1033-48. doi: 10.18632/aging.100707. Aging (Albany NY). 2014. PMID: 25564763 Free PMC article.

3

Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations.

Rozhok AI, DeGregori J. Rozhok AI, et al. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):8914-21. doi: 10.1073/pnas.1501713112. Proc Natl Acad Sci U S A. 2015. PMID: 26195756 Free PMC article.

4

A generalized theory of age-dependent carcinogenesis.

Rozhok A, DeGregori J. Rozhok A, et al. Elife. 2019 Apr 29;8:e39950. doi: 10.7554/eLife.39950. Elife. 2019. PMID: 31034356 Free PMC article.

5

Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia.

Rozhok AI, Salstrom JL, DeGregori J. Rozhok AI, et al. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1050-5. doi: 10.1073/pnas.1509333113. Epub 2016 Jan 11. Proc Natl Acad Sci U S A. 2016. PMID: 26755588 Free PMC article.

6

The evolution of lifespan and age-dependent cancer risk.

Rozhok AI, DeGregori J. Rozhok AI, et al. Trends Cancer. 2016 Oct;2(10):552-560. doi: 10.1016/j.trecan.2016.09.004. Trends Cancer. 2016. PMID: 28439564 Free PMC article.

7

Urea Cycle Sustains Cellular Energetics upon EGFR Inhibition in EGFR-Mutant NSCLC.

Pham-Danis C, Gehrke S, Danis E, Rozhok AI, Daniels MW, Gao D, Collins C, Paola JTD, D'Alessandro A, DeGregori J. Pham-Danis C, et al. Among authors: rozhok ai. Mol Cancer Res. 2019 Jun;17(6):1351-1364. doi: 10.1158/1541-7786.MCR-18-1068. Epub 2019 Feb 26. Mol Cancer Res. 2019. PMID: 30808730 Free PMC article.

8

A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution.

Rozhok AI, Silberman RE, Higa KC, Liggett LA, Amon A, DeGregori J. Rozhok AI, et al. Sci Rep. 2020 Jul 22;10(1):12198. doi: 10.1038/s41598-020-68729-1. Sci Rep. 2020. PMID: 32699207 Free PMC article.

9

The three dimensions of somatic evolution: Integrating the role of genetic damage, life-history traits, and aging in carcinogenesis.

Rozhok AI, DeGregori J. Rozhok AI, et al. Evol Appl. 2020 Mar 20;13(7):1569-1580. doi: 10.1111/eva.12947. eCollection 2020 Aug. Evol Appl. 2020. PMID: 32821273 Free PMC article.

10

Contrasting roles for C/EBPα and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects.

Fleenor CJ, Rozhok AI, Zaberezhnyy V, Mathew D, Kim J, Tan AC, Bernstein ID, DeGregori J. Fleenor CJ, et al. Among authors: rozhok ai. Stem Cells. 2015 Apr;33(4):1345-58. doi: 10.1002/stem.1936. Stem Cells. 2015. PMID: 25546133 Free PMC article.

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