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Page 1
FDA Approval Summary: Selpercatinib for the Treatment of Lung and Thyroid Cancers with RET Gene Mutations or Fusions.
Bradford D, Larkins E, Mushti SL, Rodriguez L, Skinner AM, Helms WS, Price LSL, Zirkelbach JF, Li Y, Liu J, Charlab R, Turcu FR, Liang D, Ghosh S, Roscoe D, Philip R, Zack-Taylor A, Tang S, Kluetz PG, Beaver JA, Pazdur R, Theoret MR, Singh H. Bradford D, et al. Clin Cancer Res. 2021 Apr 15;27(8):2130-2135. doi: 10.1158/1078-0432.CCR-20-3558. Epub 2020 Nov 25. Clin Cancer Res. 2021. PMID: 33239432
Weighing the Evidence: Variant Classification and Interpretation in Precision Oncology, US Food and Drug Administration Public Workshop-Workshop Proceedings.
Horne HN, Roscoe D, Litwack ED, Pathak A, Pandey JP, Gallagher PS, Koontz LM, Schuck RN, Lee EY, Hu YF, Beaver JA, Blumenthal GM, Philip R. Horne HN, et al. JCO Precis Oncol. 2019 Mar 19;3:PO.18.00314. doi: 10.1200/PO.18.00314. eCollection 2019. JCO Precis Oncol. 2019. PMID: 32914013 Free PMC article.
Protein-based multiplex assays: mock presubmissions to the US Food and Drug Administration.
Regnier FE, Skates SJ, Mesri M, Rodriguez H, Tezak Z, Kondratovich MV, Alterman MA, Levin JD, Roscoe D, Reilly E, Callaghan J, Kelm K, Brown D, Philip R, Carr SA, Liebler DC, Fisher SJ, Tempst P, Hiltke T, Kessler LG, Kinsinger CR, Ransohoff DF, Mansfield E, Anderson NL. Regnier FE, et al. Clin Chem. 2010 Feb;56(2):165-71. doi: 10.1373/clinchem.2009.140087. Epub 2009 Dec 10. Clin Chem. 2010. PMID: 20007858
FDA approval summary: vemurafenib for treatment of unresectable or metastatic melanoma with the BRAFV600E mutation.
Kim G, McKee AE, Ning YM, Hazarika M, Theoret M, Johnson JR, Xu QC, Tang S, Sridhara R, Jiang X, He K, Roscoe D, McGuinn WD, Helms WS, Russell AM, Miksinski SP, Zirkelbach JF, Earp J, Liu Q, Ibrahim A, Justice R, Pazdur R. Kim G, et al. Clin Cancer Res. 2014 Oct 1;20(19):4994-5000. doi: 10.1158/1078-0432.CCR-14-0776. Epub 2014 Aug 5. Clin Cancer Res. 2014. PMID: 25096067 Review.
Protamine folds DNA into flowers and loop stacks.
McMillan RB, Bediako H, Devenica LM, Velasquez A, Hardy IP, Ma YE, Roscoe DM, Carter AR. McMillan RB, et al. Among authors: roscoe dm. Biophys J. 2023 Nov 7;122(21):4288-4302. doi: 10.1016/j.bpj.2023.10.003. Epub 2023 Oct 6. Biophys J. 2023. PMID: 37803830 Free PMC article.
Phage display of disulfide-stabilized Fv fragments.
Brinkmann U, Chowdhury PS, Roscoe DM, Pastan I. Brinkmann U, et al. Among authors: roscoe dm. J Immunol Methods. 1995 May 11;182(1):41-50. doi: 10.1016/0022-1759(95)00016-4. J Immunol Methods. 1995. PMID: 7769243
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