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Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma.
Guislain A, Gadiot J, Kaiser A, Jordanova ES, Broeks A, Sanders J, van Boven H, de Gruijl TD, Haanen JB, Bex A, Blank CU. Guislain A, et al. Cancer Immunol Immunother. 2015 Oct;64(10):1241-50. doi: 10.1007/s00262-015-1735-z. Epub 2015 Jun 24. Cancer Immunol Immunother. 2015. PMID: 26105626 Free PMC article.
Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile.
De Groot R, Van Loenen MM, Guislain A, Nicolet BP, Freen-Van Heeren JJ, Verhagen OJHM, Van Den Heuvel MM, De Jong J, Burger P, Van Der Schoot CE, Spaapen RM, Amsen D, Haanen JBAG, Monkhorst K, Hartemink KJ, Wolkers MC. De Groot R, et al. Among authors: guislain a. Oncoimmunology. 2019 Aug 15;8(11):e1648170. doi: 10.1080/2162402X.2019.1648170. eCollection 2019. Oncoimmunology. 2019. PMID: 31646094 Free PMC article.
Effective generation of tumor-infiltrating lymphocyte products from metastatic non-small-cell lung cancer (NSCLC) lesions irrespective of location and previous treatments.
Castenmiller SM, de Groot R, Guislain A, Monkhorst K, Hartemink KJ, Veenhof AAFA, Smit EF, Haanen JBAG, Wolkers MC. Castenmiller SM, et al. Among authors: guislain a. Immunooncol Technol. 2022 Jun 22;15:100090. doi: 10.1016/j.iotech.2022.100090. eCollection 2022 Sep. Immunooncol Technol. 2022. PMID: 35965844 Free PMC article.
Tertiary lymphoid structure-related immune infiltrates in NSCLC tumor lesions correlate with low tumor-reactivity of TIL products.
Castenmiller SM, Kanagasabesan N, Guislain A, Nicolet BP, van Loenen MM, Monkhorst K, Veenhof AAFA, Smit EF, Hartemink KJ, Haanen JBAG, de Groot R, Wolkers MC. Castenmiller SM, et al. Among authors: guislain a. Oncoimmunology. 2024 Aug 22;13(1):2392898. doi: 10.1080/2162402X.2024.2392898. eCollection 2024. Oncoimmunology. 2024. PMID: 39188755 Free PMC article.
36 results