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Page 1
Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration.
Ferrés-Coy A, Galofré M, Pilar-Cuéllar F, Vidal R, Paz V, Ruiz-Bronchal E, Campa L, Pazos Á, Caso JR, Leza JC, Alvarado G, Montefeltro A, Valdizán EM, Artigas F, Bortolozzi A. Ferrés-Coy A, et al. Among authors: paz v. Mol Psychiatry. 2016 Mar;21(3):328-38. doi: 10.1038/mp.2015.80. Epub 2015 Jun 23. Mol Psychiatry. 2016. PMID: 26100539 Free PMC article.
Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys.
Alarcón-Arís D, Pavia-Collado R, Miquel-Rio L, Coppola-Segovia V, Ferrés-Coy A, Ruiz-Bronchal E, Galofré M, Paz V, Campa L, Revilla R, Montefeltro A, Kordower JH, Vila M, Artigas F, Bortolozzi A. Alarcón-Arís D, et al. Among authors: paz v. EBioMedicine. 2020 Sep;59:102944. doi: 10.1016/j.ebiom.2020.102944. Epub 2020 Aug 15. EBioMedicine. 2020. PMID: 32810825 Free PMC article.
Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
Pavia-Collado R, Cóppola-Segovia V, Miquel-Rio L, Alarcón-Aris D, Rodríguez-Aller R, Torres-López M, Paz V, Ruiz-Bronchal E, Campa L, Artigas F, Montefeltro A, Revilla R, Bortolozzi A. Pavia-Collado R, et al. Among authors: paz v. Int J Mol Sci. 2021 Mar 13;22(6):2939. doi: 10.3390/ijms22062939. Int J Mol Sci. 2021. PMID: 33805843 Free PMC article.
mTOR Knockdown in the Infralimbic Cortex Evokes A Depressive-like State in Mouse.
Garro-Martínez E, Fullana MN, Florensa-Zanuy E, Senserrich J, Paz V, Ruiz-Bronchal E, Adell A, Castro E, Díaz Á, Pazos Á, Bortolozzi A, Pilar-Cuéllar F. Garro-Martínez E, et al. Among authors: paz v. Int J Mol Sci. 2021 Aug 12;22(16):8671. doi: 10.3390/ijms22168671. Int J Mol Sci. 2021. PMID: 34445375 Free PMC article.
Corrigendum to "Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys" [EBioMedicine 2020; 59:102944].
Alarcón-Arís D, Pavia-Collado R, Miquel-Rio L, Coppola-Segovia V, Ferrés-Coy A, Ruiz-Bronchal E, Galofré M, Paz V, Campa L, Revilla R, Montefeltro A, Kordower JH, Vila M, Artigas F, Bortolozzi A. Alarcón-Arís D, et al. Among authors: paz v. EBioMedicine. 2021 Dec;74:103731. doi: 10.1016/j.ebiom.2021.103731. Epub 2021 Nov 29. EBioMedicine. 2021. PMID: 34852293 Free PMC article. No abstract available.
Human α-synuclein overexpression in mouse serotonin neurons triggers a depressive-like phenotype. Rescue by oligonucleotide therapy.
Miquel-Rio L, Alarcón-Arís D, Torres-López M, Cóppola-Segovia V, Pavia-Collado R, Paz V, Ruiz-Bronchal E, Campa L, Casal C, Montefeltro A, Vila M, Artigas F, Revilla R, Bortolozzi A. Miquel-Rio L, et al. Among authors: paz v. Transl Psychiatry. 2022 Feb 24;12(1):79. doi: 10.1038/s41398-022-01842-z. Transl Psychiatry. 2022. PMID: 35210396 Free PMC article.
104 results