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Page 1
Bromodomain inhibitors regulate the C9ORF72 locus in ALS.
Zeier Z, Esanov R, Belle KC, Volmar CH, Johnstone AL, Halley P, DeRosa BA, Khoury N, van Blitterswijk M, Rademakers R, Albert J, Brothers SP, Wuu J, Dykxhoorn DM, Benatar M, Wahlestedt C. Zeier Z, et al. Among authors: johnstone al. Exp Neurol. 2015 Sep;271:241-50. doi: 10.1016/j.expneurol.2015.06.017. Epub 2015 Jun 20. Exp Neurol. 2015. PMID: 26099177 Free PMC article.
BET bromodomain proteins are required for glioblastoma cell proliferation.
Pastori C, Daniel M, Penas C, Volmar CH, Johnstone AL, Brothers SP, Graham RM, Allen B, Sarkaria JN, Komotar RJ, Wahlestedt C, Ayad NG. Pastori C, et al. Among authors: johnstone al. Epigenetics. 2014 Apr;9(4):611-20. doi: 10.4161/epi.27906. Epub 2014 Feb 19. Epigenetics. 2014. PMID: 24496381 Free PMC article.
Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways.
Johnstone AL, Andrade NS, Barbier E, Khomtchouk BB, Rienas CA, Lowe K, Van Booven DJ, Domi E, Esanov R, Vilca S, Tapocik JD, Rodriguez K, Maryanski D, Keogh MC, Meinhardt MW, Sommer WH, Heilig M, Zeier Z, Wahlestedt C. Johnstone AL, et al. Addict Biol. 2021 Jan;26(1):e12816. doi: 10.1111/adb.12816. Epub 2019 Aug 1. Addict Biol. 2021. PMID: 31373129 Free PMC article.
Dependence-induced increase of alcohol self-administration and compulsive drinking mediated by the histone methyltransferase PRDM2.
Barbier E, Johnstone AL, Khomtchouk BB, Tapocik JD, Pitcairn C, Rehman F, Augier E, Borich A, Schank JR, Rienas CA, Van Booven DJ, Sun H, Nätt D, Wahlestedt C, Heilig M. Barbier E, et al. Among authors: johnstone al. Mol Psychiatry. 2017 Dec;22(12):1746-1758. doi: 10.1038/mp.2016.131. Epub 2016 Aug 30. Mol Psychiatry. 2017. PMID: 27573876 Free PMC article.
Reprogramming of mPFC transcriptome and function in alcohol dependence.
Heilig M, Barbier E, Johnstone AL, Tapocik J, Meinhardt MW, Pfarr S, Wahlestedt C, Sommer WH. Heilig M, et al. Among authors: johnstone al. Genes Brain Behav. 2017 Jan;16(1):86-100. doi: 10.1111/gbb.12344. Epub 2016 Nov 24. Genes Brain Behav. 2017. PMID: 27657733 Free PMC article. Review.
Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies.
Shah RN, Grzybowski AT, Cornett EM, Johnstone AL, Dickson BM, Boone BA, Cheek MA, Cowles MW, Maryanski D, Meiners MJ, Tiedemann RL, Vaughan RM, Arora N, Sun ZW, Rothbart SB, Keogh MC, Ruthenburg AJ. Shah RN, et al. Among authors: johnstone al. Mol Cell. 2018 Oct 4;72(1):162-177.e7. doi: 10.1016/j.molcel.2018.08.015. Epub 2018 Sep 20. Mol Cell. 2018. PMID: 30244833 Free PMC article.
21 results