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Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal.
Rabenhorst U, Thalheimer FB, Gerlach K, Kijonka M, Böhm S, Krause DS, Vauti F, Arnold HH, Schroeder T, Schnütgen F, von Melchner H, Rieger MA, Zörnig M. Rabenhorst U, et al. Among authors: gerlach k. Cell Rep. 2015 Jun 30;11(12):1847-55. doi: 10.1016/j.celrep.2015.05.038. Epub 2015 Jun 18. Cell Rep. 2015. PMID: 26095368 Free article.
Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE.
Khageh Hosseini S, Kolterer S, Steiner M, von Manstein V, Gerlach K, Trojan J, Waidmann O, Zeuzem S, Schulze JO, Hahn S, Steinhilber D, Gatterdam V, Tampé R, Biondi RM, Proschak E, Zörnig M. Khageh Hosseini S, et al. Among authors: gerlach k. Biochem Pharmacol. 2017 Dec 15;146:53-62. doi: 10.1016/j.bcp.2017.10.003. Epub 2017 Oct 13. Biochem Pharmacol. 2017. PMID: 29031818
The transcriptional regulator FUBP1 influences disease outcome in murine and human myeloid leukemia.
Hoang VT, Verma D, Godavarthy PS, Llavona P, Steiner M, Gerlach K, Michels BE, Bohnenberger H, Wachter A, Oellerich T, Müller-Kuller U, Weissenberger E, Voutsinas JM, Oehler VG, Farin HF, Zörnig M, Krause DS. Hoang VT, et al. Among authors: gerlach k. Leukemia. 2019 Jul;33(7):1700-1712. doi: 10.1038/s41375-018-0358-8. Epub 2019 Jan 11. Leukemia. 2019. PMID: 30635626
FUSE binding protein 1 (FUBP1) expression is upregulated by T-cell acute lymphocytic leukemia protein 1 (TAL1) and required for efficient erythroid differentiation.
Steiner M, Schneider L, Yillah J, Gerlach K, Kuvardina ON, Meyer A, Maring A, Bonig H, Seifried E, Zörnig M, Lausen J. Steiner M, et al. Among authors: gerlach k. PLoS One. 2019 Jan 17;14(1):e0210515. doi: 10.1371/journal.pone.0210515. eCollection 2019. PLoS One. 2019. PMID: 30653565 Free PMC article.
A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function.
Kälin S, Becker M, Ott VB, Serr I, Hosp F, Mollah MMH, Keipert S, Lamp D, Rohner-Jeanrenaud F, Flynn VK, Scherm MG, Nascimento LFR, Gerlach K, Popp V, Dietzen S, Bopp T, Krishnamurthy P, Kaplan MH, Serrano M, Woods SC, Tripal P, Palmisano R, Jastroch M, Blüher M, Wolfrum C, Weigmann B, Ziegler AG, Mann M, Tschöp MH, Daniel C. Kälin S, et al. Among authors: gerlach k. Cell Metab. 2017 Sep 5;26(3):475-492.e7. doi: 10.1016/j.cmet.2017.08.008. Cell Metab. 2017. PMID: 28877454 Free PMC article.
Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis.
Tang Y, Reissig S, Glasmacher E, Regen T, Wanke F, Nikolaev A, Gerlach K, Popp V, Karram K, Fantini MC, Schattenberg JM, Galle PR, Neurath MF, Weigmann B, Kurschus FC, Hövelmeyer N, Waisman A. Tang Y, et al. Among authors: gerlach k. Gastroenterology. 2019 Feb;156(3):692-707.e7. doi: 10.1053/j.gastro.2018.10.023. Epub 2018 Oct 10. Gastroenterology. 2019. PMID: 30315770
296 results