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Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation.
Chen K, Hu J, Moore DL, Liu R, Kessans SA, Breslin K, Lucet IS, Keniry A, Leong HS, Parish CL, Hilton DJ, Lemmers RJ, van der Maarel SM, Czabotar PE, Dobson RC, Ritchie ME, Kay GF, Murphy JM, Blewitt ME. Chen K, et al. Among authors: murphy jm. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3535-44. doi: 10.1073/pnas.1504232112. Epub 2015 Jun 19. Proc Natl Acad Sci U S A. 2015. PMID: 26091879 Free PMC article.
Critical roles for c-Myb in lymphoid priming and early B-cell development.
Greig KT, de Graaf CA, Murphy JM, Carpinelli MR, Pang SH, Frampton J, Kile BT, Hilton DJ, Nutt SL. Greig KT, et al. Among authors: murphy jm. Blood. 2010 Apr 8;115(14):2796-805. doi: 10.1182/blood-2009-08-239210. Epub 2010 Feb 3. Blood. 2010. PMID: 20130238 Free PMC article.
Epigenetic regulator Smchd1 functions as a tumor suppressor.
Leong HS, Chen K, Hu Y, Lee S, Corbin J, Pakusch M, Murphy JM, Majewski IJ, Smyth GK, Alexander WS, Hilton DJ, Blewitt ME. Leong HS, et al. Among authors: murphy jm. Cancer Res. 2013 Mar 1;73(5):1591-9. doi: 10.1158/0008-5472.CAN-12-3019. Epub 2012 Dec 26. Cancer Res. 2013. PMID: 23269277
Regulation of Janus kinases by SOCS proteins.
Kershaw NJ, Murphy JM, Lucet IS, Nicola NA, Babon JJ. Kershaw NJ, et al. Among authors: murphy jm. Biochem Soc Trans. 2013 Aug;41(4):1042-7. doi: 10.1042/BST20130077. Biochem Soc Trans. 2013. PMID: 23863176 Free PMC article. Review.
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.
Murphy JM, Czabotar PE, Hildebrand JM, Lucet IS, Zhang JG, Alvarez-Diaz S, Lewis R, Lalaoui N, Metcalf D, Webb AI, Young SN, Varghese LN, Tannahill GM, Hatchell EC, Majewski IJ, Okamoto T, Dobson RC, Hilton DJ, Babon JJ, Nicola NA, Strasser A, Silke J, Alexander WS. Murphy JM, et al. Immunity. 2013 Sep 19;39(3):443-53. doi: 10.1016/j.immuni.2013.06.018. Epub 2013 Sep 5. Immunity. 2013. PMID: 24012422 Free article.
795 results