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Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases.
Oftedal BE, Hellesen A, Erichsen MM, Bratland E, Vardi A, Perheentupa J, Kemp EH, Fiskerstrand T, Viken MK, Weetman AP, Fleishman SJ, Banka S, Newman WG, Sewell WA, Sozaeva LS, Zayats T, Haugarvoll K, Orlova EM, Haavik J, Johansson S, Knappskog PM, Løvås K, Wolff AS, Abramson J, Husebye ES. Oftedal BE, et al. Among authors: fleishman sj. Immunity. 2015 Jun 16;42(6):1185-96. doi: 10.1016/j.immuni.2015.04.021. Immunity. 2015. PMID: 26084028 Free article.
Computational optimization of antibody humanness and stability by systematic energy-based ranking.
Tennenhouse A, Khmelnitsky L, Khalaila R, Yeshaya N, Noronha A, Lindzen M, Makowski EK, Zaretsky I, Sirkis YF, Galon-Wolfenson Y, Tessier PM, Abramson J, Yarden Y, Fass D, Fleishman SJ. Tennenhouse A, et al. Among authors: fleishman sj. Nat Biomed Eng. 2024 Jan;8(1):30-44. doi: 10.1038/s41551-023-01079-1. Epub 2023 Aug 7. Nat Biomed Eng. 2024. PMID: 37550425 Free PMC article.
Computational design of protein-protein interactions.
Schreiber G, Fleishman SJ. Schreiber G, et al. Among authors: fleishman sj. Curr Opin Struct Biol. 2013 Dec;23(6):903-10. doi: 10.1016/j.sbi.2013.08.003. Epub 2013 Aug 29. Curr Opin Struct Biol. 2013. PMID: 23993666 Review.
Addressing epistasis in the design of protein function.
Lipsh-Sokolik R, Fleishman SJ. Lipsh-Sokolik R, et al. Among authors: fleishman sj. Proc Natl Acad Sci U S A. 2024 Aug 20;121(34):e2314999121. doi: 10.1073/pnas.2314999121. Epub 2024 Aug 12. Proc Natl Acad Sci U S A. 2024. PMID: 39133844 Free PMC article.
Community-wide assessment of protein-interface modeling suggests improvements to design methodology.
Fleishman SJ, Whitehead TA, Strauch EM, Corn JE, Qin S, Zhou HX, Mitchell JC, Demerdash ON, Takeda-Shitaka M, Terashi G, Moal IH, Li X, Bates PA, Zacharias M, Park H, Ko JS, Lee H, Seok C, Bourquard T, Bernauer J, Poupon A, Azé J, Soner S, Ovali SK, Ozbek P, Tal NB, Haliloglu T, Hwang H, Vreven T, Pierce BG, Weng Z, Pérez-Cano L, Pons C, Fernández-Recio J, Jiang F, Yang F, Gong X, Cao L, Xu X, Liu B, Wang P, Li C, Wang C, Robert CH, Guharoy M, Liu S, Huang Y, Li L, Guo D, Chen Y, Xiao Y, London N, Itzhaki Z, Schueler-Furman O, Inbar Y, Potapov V, Cohen M, Schreiber G, Tsuchiya Y, Kanamori E, Standley DM, Nakamura H, Kinoshita K, Driggers CM, Hall RG, Morgan JL, Hsu VL, Zhan J, Yang Y, Zhou Y, Kastritis PL, Bonvin AM, Zhang W, Camacho CJ, Kilambi KP, Sircar A, Gray JJ, Ohue M, Uchikoga N, Matsuzaki Y, Ishida T, Akiyama Y, Khashan R, Bush S, Fouches D, Tropsha A, Esquivel-Rodríguez J, Kihara D, Stranges PB, Jacak R, Kuhlman B, Huang SY, Zou X, Wodak SJ, Janin J, Baker D. Fleishman SJ, et al. J Mol Biol. 2011 Nov 25;414(2):289-302. doi: 10.1016/j.jmb.2011.09.031. Epub 2011 Sep 29. J Mol Biol. 2011. PMID: 22001016 Free PMC article.
133 results