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Page 1
ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth.
Mitchell D, Pobre EG, Mulivor AW, Grinberg AV, Castonguay R, Monnell TE, Solban N, Ucran JA, Pearsall RS, Underwood KW, Seehra J, Kumar R. Mitchell D, et al. Among authors: mulivor aw. Mol Cancer Ther. 2010 Feb;9(2):379-88. doi: 10.1158/1535-7163.MCT-09-0650. Epub 2010 Feb 2. Mol Cancer Ther. 2010. PMID: 20124460
Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth.
Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV. Castonguay R, et al. Among authors: mulivor aw. J Biol Chem. 2011 Aug 26;286(34):30034-46. doi: 10.1074/jbc.M111.260133. Epub 2011 Jul 7. J Biol Chem. 2011. PMID: 21737454 Free PMC article.
Follistatin-288-Fc Fusion Protein Promotes Localized Growth of Skeletal Muscle.
Castonguay R, Lachey J, Wallner S, Strand J, Liharska K, Watanabe AE, Cannell M, Davies MV, Sako D, Troy ME, Krishnan L, Mulivor AW, Li H, Keates S, Alexander MJ, Pearsall RS, Kumar R. Castonguay R, et al. Among authors: mulivor aw. J Pharmacol Exp Ther. 2019 Mar;368(3):435-445. doi: 10.1124/jpet.118.252304. Epub 2018 Dec 18. J Pharmacol Exp Ther. 2019. PMID: 30563942
Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease.
Pearsall RS, Davies MV, Cannell M, Li J, Widrick J, Mulivor AW, Wallner S, Troy ME, Spaits M, Liharska K, Sako D, Castonguay R, Keates S, Grinberg AV, Suragani RNVS, Kumar R. Pearsall RS, et al. Among authors: mulivor aw. Sci Rep. 2019 Aug 6;9(1):11392. doi: 10.1038/s41598-019-47818-w. Sci Rep. 2019. PMID: 31388039 Free PMC article.
Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo.
Chantry AD, Heath D, Mulivor AW, Pearsall S, Baud'huin M, Coulton L, Evans H, Abdul N, Werner ED, Bouxsein ML, Key ML, Seehra J, Arnett TR, Vanderkerken K, Croucher P. Chantry AD, et al. Among authors: mulivor aw. J Bone Miner Res. 2010 Dec;25(12):2633-46. doi: 10.1002/jbmr.142. Epub 2010 Jun 7. J Bone Miner Res. 2010. PMID: 20533325 Free article.
11 results