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Catalytic in vivo protein knockdown by small-molecule PROTACs.
Bondeson DP, Mares A, Smith IE, Ko E, Campos S, Miah AH, Mulholland KE, Routly N, Buckley DL, Gustafson JL, Zinn N, Grandi P, Shimamura S, Bergamini G, Faelth-Savitski M, Bantscheff M, Cox C, Gordon DA, Willard RR, Flanagan JJ, Casillas LN, Votta BJ, den Besten W, Famm K, Kruidenier L, Carter PS, Harling JD, Churcher I, Crews CM. Bondeson DP, et al. Among authors: famm k. Nat Chem Biol. 2015 Aug;11(8):611-7. doi: 10.1038/nchembio.1858. Epub 2015 Jun 10. Nat Chem Biol. 2015. PMID: 26075522 Free PMC article.
Drug discovery: a jump-start for electroceuticals.
Famm K, Litt B, Tracey KJ, Boyden ES, Slaoui M. Famm K, et al. Nature. 2013 Apr 11;496(7444):159-61. doi: 10.1038/496159a. Nature. 2013. PMID: 23579662 Free PMC article. No abstract available.
Bioelectronic medicines: a research roadmap.
Birmingham K, Gradinaru V, Anikeeva P, Grill WM, Pikov V, McLaughlin B, Pasricha P, Weber D, Ludwig K, Famm K. Birmingham K, et al. Among authors: famm k. Nat Rev Drug Discov. 2014 Jun;13(6):399-400. doi: 10.1038/nrd4351. Nat Rev Drug Discov. 2014. PMID: 24875080 Free article. Review. No abstract available.
Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes.
Sacramento JF, Chew DJ, Melo BF, Donegá M, Dopson W, Guarino MP, Robinson A, Prieto-Lloret J, Patel S, Holinski BJ, Ramnarain N, Pikov V, Famm K, Conde SV. Sacramento JF, et al. Among authors: famm k. Diabetologia. 2018 Mar;61(3):700-710. doi: 10.1007/s00125-017-4533-7. Epub 2018 Jan 14. Diabetologia. 2018. PMID: 29332196 Free PMC article.
13 results