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Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.
Cha-Molstad H, Sung KS, Hwang J, Kim KA, Yu JE, Yoo YD, Jang JM, Han DH, Molstad M, Kim JG, Lee YJ, Zakrzewska A, Kim SH, Kim ST, Kim SY, Lee HG, Soung NK, Ahn JS, Ciechanover A, Kim BY, Kwon YT. Cha-Molstad H, et al. Among authors: kim st, kim sh, kim ka, kim sy, kim by, kim jg. Nat Cell Biol. 2015 Jul;17(7):917-29. doi: 10.1038/ncb3177. Epub 2015 Jun 15. Nat Cell Biol. 2015. PMID: 26075355 Free PMC article.
The N-end rule proteolytic system in autophagy.
Kim ST, Tasaki T, Zakrzewska A, Yoo YD, Sa Sung K, Kim SH, Cha-Molstad H, Hwang J, Kim KA, Kim BY, Kwon YT. Kim ST, et al. Among authors: kim sh, kim ka, kim by. Autophagy. 2013 Jul;9(7):1100-3. doi: 10.4161/auto.24643. Epub 2013 Apr 15. Autophagy. 2013. PMID: 23628846 Free PMC article.
p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis.
Cha-Molstad H, Yu JE, Feng Z, Lee SH, Kim JG, Yang P, Han B, Sung KW, Yoo YD, Hwang J, McGuire T, Shim SM, Song HD, Ganipisetti S, Wang N, Jang JM, Lee MJ, Kim SJ, Lee KH, Hong JT, Ciechanover A, Mook-Jung I, Kim KP, Xie XQ, Kwon YT, Kim BY. Cha-Molstad H, et al. Among authors: kim kp, kim sj, kim by, kim jg. Nat Commun. 2017 Jul 24;8(1):102. doi: 10.1038/s41467-017-00085-7. Nat Commun. 2017. PMID: 28740232 Free PMC article.
N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
Yoo YD, Mun SR, Ji CH, Sung KW, Kang KY, Heo AJ, Lee SH, An JY, Hwang J, Xie XQ, Ciechanover A, Kim BY, Kwon YT. Yoo YD, et al. Among authors: kim by. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2716-E2724. doi: 10.1073/pnas.1719110115. Epub 2018 Mar 5. Proc Natl Acad Sci U S A. 2018. PMID: 29507222 Free PMC article.
The N-Degron Pathway Mediates ER-phagy.
Ji CH, Kim HY, Heo AJ, Lee SH, Lee MJ, Kim SB, Srinivasrao G, Mun SR, Cha-Molstad H, Ciechanover A, Choi CY, Lee HG, Kim BY, Kwon YT. Ji CH, et al. Among authors: kim sb, kim hy, kim by. Mol Cell. 2019 Sep 5;75(5):1058-1072.e9. doi: 10.1016/j.molcel.2019.06.028. Epub 2019 Jul 30. Mol Cell. 2019. PMID: 31375263 Free article.
1,361 results