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Lactate Mediates the Effects of Exercise on Learning and Memory through SIRT1-Dependent Activation of Hippocampal Brain-Derived Neurotrophic Factor (BDNF).
El Hayek L, Khalifeh M, Zibara V, Abi Assaad R, Emmanuel N, Karnib N, El-Ghandour R, Nasrallah P, Bilen M, Ibrahim P, Younes J, Abou Haidar E, Barmo N, Jabre V, Stephan JS, Sleiman SF. El Hayek L, et al. Among authors: stephan js. J Neurosci. 2019 Mar 27;39(13):2369-2382. doi: 10.1523/JNEUROSCI.1661-18.2019. Epub 2019 Jan 28. J Neurosci. 2019. PMID: 30692222 Free PMC article.
Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases.
Karnib N, El-Ghandour R, El Hayek L, Nasrallah P, Khalifeh M, Barmo N, Jabre V, Ibrahim P, Bilen M, Stephan JS, Holson EB, Ratan RR, Sleiman SF. Karnib N, et al. Among authors: stephan js. Neuropsychopharmacology. 2019 May;44(6):1152-1162. doi: 10.1038/s41386-019-0313-z. Epub 2019 Jan 8. Neuropsychopharmacology. 2019. PMID: 30647450 Free PMC article.
Nicotine induces resilience to chronic social defeat stress in a mouse model of water pipe tobacco exposure by activating BDNF signaling.
Khalifeh M, Hobeika R, El Hayek L, Saad J, Eid F, El-Khoury R, Ghayad LM, Jabre V, Nasrallah P, Barmo N, Stephan JS, Khnayzer R, Khalil C, Sleiman SF. Khalifeh M, et al. Among authors: stephan js. Behav Brain Res. 2020 Mar 16;382:112499. doi: 10.1016/j.bbr.2020.112499. Epub 2020 Jan 21. Behav Brain Res. 2020. PMID: 31978493
Epigenetic changes in diabetes.
Al-Haddad R, Karnib N, Assaad RA, Bilen Y, Emmanuel N, Ghanem A, Younes J, Zibara V, Stephan JS, Sleiman SF. Al-Haddad R, et al. Among authors: stephan js. Neurosci Lett. 2016 Jun 20;625:64-9. doi: 10.1016/j.neulet.2016.04.046. Epub 2016 Apr 27. Neurosci Lett. 2016. PMID: 27130819 Review.
Branched-chain amino acids mediate resilience to chronic social defeat stress by activating BDNF/TRKB signaling.
Nasrallah P, Haidar EA, Stephan JS, El Hayek L, Karnib N, Khalifeh M, Barmo N, Jabre V, Houbeika R, Ghanem A, Nasser J, Zeeni N, Bassil M, Sleiman SF. Nasrallah P, et al. Among authors: stephan js. Neurobiol Stress. 2019 May 14;11:100170. doi: 10.1016/j.ynstr.2019.100170. eCollection 2019 Nov. Neurobiol Stress. 2019. PMID: 31193350 Free PMC article.
23 results