Hanlon SP - Search Results

1

Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis.

Geier M, Bachler T, Hanlon SP, Eggimann FK, Kittelmann M, Weber H, Lütz S, Wirz B, Winkler M. Geier M, et al. Among authors: hanlon sp. Microb Cell Fact. 2015 Jun 12;14:82. doi: 10.1186/s12934-015-0262-0. Microb Cell Fact. 2015. PMID: 26062974 Free PMC article.

2

Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scale.

Hanlon SP, Camattari A, Abad S, Glieder A, Kittelmann M, Lütz S, Wirz B, Winkler M. Hanlon SP, et al. Chem Commun (Camb). 2012 Jun 18;48(48):6001-3. doi: 10.1039/c2cc17878h. Epub 2012 May 10. Chem Commun (Camb). 2012. PMID: 22576266

3

Human xanthine oxidase recombinant in E. coli: A whole cell catalyst for preparative drug metabolite synthesis.

Ferreira Antunes M, Eggimann FK, Kittelmann M, Lütz S, Hanlon SP, Wirz B, Bachler T, Winkler M. Ferreira Antunes M, et al. Among authors: hanlon sp. J Biotechnol. 2016 Oct 10;235:3-10. doi: 10.1016/j.jbiotec.2016.03.045. Epub 2016 Mar 25. J Biotechnol. 2016. PMID: 27021957 Review.

4

Human Enzymes for Organic Synthesis.

Winkler M, Geier M, Hanlon SP, Nidetzky B, Glieder A. Winkler M, et al. Among authors: hanlon sp. Angew Chem Int Ed Engl. 2018 Oct 8;57(41):13406-13423. doi: 10.1002/anie.201800678. Epub 2018 Sep 11. Angew Chem Int Ed Engl. 2018. PMID: 29600541 Free PMC article. Review.

5

Protein-engineering of an amine transaminase for the stereoselective synthesis of a pharmaceutically relevant bicyclic amine.

Weiß MS, Pavlidis IV, Spurr P, Hanlon SP, Wirz B, Iding H, Bornscheuer UT. Weiß MS, et al. Among authors: hanlon sp. Org Biomol Chem. 2016 Nov 2;14(43):10249-10254. doi: 10.1039/c6ob02139e. Org Biomol Chem. 2016. PMID: 27739550

6

Identification of (S)-selective transaminases for the asymmetric synthesis of bulky chiral amines.

Pavlidis IV, Weiß MS, Genz M, Spurr P, Hanlon SP, Wirz B, Iding H, Bornscheuer UT. Pavlidis IV, et al. Among authors: hanlon sp. Nat Chem. 2016 Nov;8(11):1076-1082. doi: 10.1038/nchem.2578. Epub 2016 Jul 18. Nat Chem. 2016. PMID: 27768108

7

Expanding the Imine Reductase Toolbox by Exploring the Bacterial Protein-Sequence Space.

Wetzl D, Berrera M, Sandon N, Fishlock D, Ebeling M, Müller M, Hanlon S, Wirz B, Iding H. Wetzl D, et al. Chembiochem. 2015 Aug 17;16(12):1749-56. doi: 10.1002/cbic.201500218. Epub 2015 Jul 2. Chembiochem. 2015. PMID: 26044455

8

Amine Transaminase Engineering for Spatially Bulky Substrate Acceptance.

Weiß MS, Pavlidis IV, Spurr P, Hanlon SP, Wirz B, Iding H, Bornscheuer UT. Weiß MS, et al. Among authors: hanlon sp. Chembiochem. 2017 Jun 1;18(11):1022-1026. doi: 10.1002/cbic.201700033. Epub 2017 Apr 27. Chembiochem. 2017. PMID: 28334484

9

The Swiss Industrial Biocatalysis Consortium (SIBC): Past, Present and Future.

Hanlon S. Hanlon S. Chimia (Aarau). 2020 May 27;74(5):342-344. doi: 10.2533/chimia.2020.342. Chimia (Aarau). 2020. PMID: 32482209 Free article.

10

Metabolite identification via LC-SPE-NMR-MS of the in vitro biooxidation products of a lead mGlu5 allosteric antagonist and impact on the improvement of metabolic stability in the series.

Ceccarelli SM, Schlotterbeck G, Boissin P, Binder M, Buettelmann B, Hanlon S, Jaeschke G, Kolczewski S, Kupfer E, Peters JU, Porter RH, Prinssen EP, Rueher M, Ruf I, Spooren W, Stämpfli A, Vieira E. Ceccarelli SM, et al. ChemMedChem. 2008 Jan;3(1):136-44. doi: 10.1002/cmdc.200700203. ChemMedChem. 2008. PMID: 17994660

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