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Alterations of the spindle checkpoint pathway in clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas.
Arai E, Gotoh M, Tian Y, Sakamoto H, Ono M, Matsuda A, Takahashi Y, Miyata S, Totsuka H, Chiku S, Komiyama M, Fujimoto H, Matsumoto K, Yamada T, Yoshida T, Kanai Y. Arai E, et al. Among authors: takahashi y. Int J Cancer. 2015 Dec 1;137(11):2589-606. doi: 10.1002/ijc.29630. Epub 2015 Jun 30. Int J Cancer. 2015. PMID: 26061684 Free PMC article.
Epigenetic clustering of gastric carcinomas based on DNA methylation profiles at the precancerous stage: its correlation with tumor aggressiveness and patient outcome.
Yamanoi K, Arai E, Tian Y, Takahashi Y, Miyata S, Sasaki H, Chiwaki F, Ichikawa H, Sakamoto H, Kushima R, Katai H, Yoshida T, Sakamoto M, Kanai Y. Yamanoi K, et al. Among authors: takahashi y. Carcinogenesis. 2015 May;36(5):509-20. doi: 10.1093/carcin/bgv013. Epub 2015 Mar 4. Carcinogenesis. 2015. PMID: 25740824 Free PMC article.
Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: a single-institutional methylome analysis using 1007 tissue specimens.
Ohara K, Arai E, Takahashi Y, Ito N, Shibuya A, Tsuta K, Kushima R, Tsuda H, Ojima H, Fujimoto H, Watanabe SI, Katai H, Kinoshita T, Shibata T, Kohno T, Kanai Y. Ohara K, et al. Among authors: takahashi y. Carcinogenesis. 2017 Mar 1;38(3):241-251. doi: 10.1093/carcin/bgw209. Carcinogenesis. 2017. PMID: 28069692 Free PMC article.
Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related multistage hepatocarcinogenesis: comparison with hepatitis virus-related carcinogenesis.
Kuramoto J, Arai E, Tian Y, Funahashi N, Hiramoto M, Nammo T, Nozaki Y, Takahashi Y, Ito N, Shibuya A, Ojima H, Sukeda A, Seki Y, Kasama K, Yasuda K, Kanai Y. Kuramoto J, et al. Among authors: takahashi y. Carcinogenesis. 2017 Mar 1;38(3):261-270. doi: 10.1093/carcin/bgx005. Carcinogenesis. 2017. PMID: 28426876 Free PMC article.
Aberrant DNA methylation results in altered gene expression in non-alcoholic steatohepatitis-related hepatocellular carcinomas.
Tian Y, Arai E, Makiuchi S, Tsuda N, Kuramoto J, Ohara K, Takahashi Y, Ito N, Ojima H, Hiraoka N, Gotoh M, Yoshida T, Kanai Y. Tian Y, et al. Among authors: takahashi y. J Cancer Res Clin Oncol. 2020 Oct;146(10):2461-2477. doi: 10.1007/s00432-020-03298-4. Epub 2020 Jul 19. J Cancer Res Clin Oncol. 2020. PMID: 32685988 Free PMC article.
Cooperative participation of epigenomic and genomic alterations in the clinicopathological diversity of gastric adenocarcinomas: significance of cell adhesion and epithelial-mesenchymal transition-related signaling pathways.
Yang M, Arai E, Takahashi Y, Totsuka H, Chiku S, Taniguchi H, Katai H, Sakamoto H, Yoshida T, Kanai Y. Yang M, et al. Among authors: takahashi y. Carcinogenesis. 2020 Nov 13;41(11):1473-1484. doi: 10.1093/carcin/bgaa079. Carcinogenesis. 2020. PMID: 32710740 Free PMC article.
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