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Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides.
Ezzat K, Aoki Y, Koo T, McClorey G, Benner L, Coenen-Stass A, O'Donovan L, Lehto T, Garcia-Guerra A, Nordin J, Saleh AF, Behlke M, Morris J, Goyenvalle A, Dugovic B, Leumann C, Gordon S, Gait MJ, El-Andaloussi S, Wood MJ. Ezzat K, et al. Nano Lett. 2015 Jul 8;15(7):4364-73. doi: 10.1021/acs.nanolett.5b00490. Epub 2015 Jun 15. Nano Lett. 2015. PMID: 26042553 Free PMC article.
Peptide-based matrices as drug delivery vehicles.
Ezzat K, El Andaloussi S, Abdo R, Langel U. Ezzat K, et al. Curr Pharm Des. 2010;16(9):1167-78. doi: 10.2174/138161210790963832. Curr Pharm Des. 2010. PMID: 20030616 Review.
PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation.
Ezzat K, Andaloussi SE, Zaghloul EM, Lehto T, Lindberg S, Moreno PM, Viola JR, Magdy T, Abdo R, Guterstam P, Sillard R, Hammond SM, Wood MJ, Arzumanov AA, Gait MJ, Smith CI, Hällbrink M, Langel Ü. Ezzat K, et al. Nucleic Acids Res. 2011 Jul;39(12):5284-98. doi: 10.1093/nar/gkr072. Epub 2011 Feb 23. Nucleic Acids Res. 2011. PMID: 21345932 Free PMC article.
Peptide nanoparticles for oligonucleotide delivery.
Lehto T, Ezzat K, Langel U. Lehto T, et al. Among authors: ezzat k. Prog Mol Biol Transl Sci. 2011;104:397-426. doi: 10.1016/B978-0-12-416020-0.00010-3. Prog Mol Biol Transl Sci. 2011. PMID: 22093225 Review.
PepFect14 peptide vector for efficient gene delivery in cell cultures.
Veiman KL, Mäger I, Ezzat K, Margus H, Lehto T, Langel K, Kurrikoff K, Arukuusk P, Suhorutšenko J, Padari K, Pooga M, Lehto T, Langel Ü. Veiman KL, et al. Among authors: ezzat k. Mol Pharm. 2013 Jan 7;10(1):199-210. doi: 10.1021/mp3003557. Epub 2012 Dec 14. Mol Pharm. 2013. PMID: 23186360
Synthetic SiRNA Delivery: Progress and Prospects.
Roberts TC, Ezzat K, El Andaloussi S, Weinberg MS. Roberts TC, et al. Among authors: ezzat k. Methods Mol Biol. 2016;1364:291-310. doi: 10.1007/978-1-4939-3112-5_23. Methods Mol Biol. 2016. PMID: 26472459 Review.
Peptides for nucleic acid delivery.
Lehto T, Ezzat K, Wood MJA, El Andaloussi S. Lehto T, et al. Among authors: ezzat k. Adv Drug Deliv Rev. 2016 Nov 15;106(Pt A):172-182. doi: 10.1016/j.addr.2016.06.008. Epub 2016 Jun 25. Adv Drug Deliv Rev. 2016. PMID: 27349594 Free article. Review.
47 results