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PBPK modeling of irbesartan: incorporation of hepatic uptake.
Chapy H, Klieber S, Brun P, Gerbal-Chaloin S, Boulenc X, Nicolas O. Chapy H, et al. Among authors: brun p. Biopharm Drug Dispos. 2015 Nov;36(8):491-506. doi: 10.1002/bdd.1961. Epub 2015 Aug 3. Biopharm Drug Dispos. 2015. PMID: 26037524
IMI - oral biopharmaceutics tools project - evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds.
Margolskee A, Darwich AS, Pepin X, Pathak SM, Bolger MB, Aarons L, Rostami-Hodjegan A, Angstenberger J, Graf F, Laplanche L, Müller T, Carlert S, Daga P, Murphy D, Tannergren C, Yasin M, Greschat-Schade S, Mück W, Muenster U, van der Mey D, Frank KJ, Lloyd R, Adriaenssen L, Bevernage J, De Zwart L, Swerts D, Tistaert C, Van Den Bergh A, Van Peer A, Beato S, Nguyen-Trung AT, Bennett J, McAllister M, Wong M, Zane P, Ollier C, Vicat P, Kolhmann M, Marker A, Brun P, Mazuir F, Beilles S, Venczel M, Boulenc X, Loos P, Lennernäs H, Abrahamsson B. Margolskee A, et al. Among authors: brun p. Eur J Pharm Sci. 2017 Jan 1;96:598-609. doi: 10.1016/j.ejps.2016.09.027. Epub 2016 Sep 23. Eur J Pharm Sci. 2017. PMID: 27671970
Absorption, Metabolism, and Excretion of [14C]-Tolebrutinib After Oral Administration in Humans, Contribution of the Metabolites to Pharmacological Activity.
Nicolas O, Moliner P, Soubayrol P, Vitse O, Roy S, Cabanis MJ, Turner T, Klieber S, Muccio S, Arabeyre C, Brun P. Nicolas O, et al. Among authors: brun p. Clin Drug Investig. 2023 Aug;43(8):653-665. doi: 10.1007/s40261-023-01296-1. Epub 2023 Aug 29. Clin Drug Investig. 2023. PMID: 37642857 Free PMC article.
Oral delivery of diabetes peptides - Comparing standard formulations incorporating functional excipients and nanotechnologies in the translational context.
Lakkireddy HR, Urmann M, Besenius M, Werner U, Haack T, Brun P, Alié J, Illel B, Hortala L, Vogel R, Bazile D. Lakkireddy HR, et al. Among authors: brun p. Adv Drug Deliv Rev. 2016 Nov 15;106(Pt B):196-222. doi: 10.1016/j.addr.2016.02.011. Epub 2016 Mar 8. Adv Drug Deliv Rev. 2016. PMID: 26964477 Review.
632 results