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Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.
Kim H, Frederick DT, Levesque MP, Cooper ZA, Feng Y, Krepler C, Brill L, Samuels Y, Hayward NK, Perlina A, Piris A, Zhang T, Halaban R, Herlyn MM, Brown KM, Wargo JA, Dummer R, Flaherty KT, Ronai ZA. Kim H, et al. Cell Rep. 2015 Jun 9;11(9):1458-73. doi: 10.1016/j.celrep.2015.04.049. Epub 2015 May 28. Cell Rep. 2015. PMID: 26027934 Free PMC article.
Regulators and effectors of Siah ubiquitin ligases.
Qi J, Kim H, Scortegagna M, Ronai ZA. Qi J, et al. Among authors: kim h. Cell Biochem Biophys. 2013 Sep;67(1):15-24. doi: 10.1007/s12013-013-9636-2. Cell Biochem Biophys. 2013. PMID: 23700162 Free PMC article. Review.
Fine tuning of the UPR by the ubiquitin ligases Siah1/2.
Scortegagna M, Kim H, Li JL, Yao H, Brill LM, Han J, Lau E, Bowtell D, Haddad G, Kaufman RJ, Ronai ZA. Scortegagna M, et al. Among authors: kim h. PLoS Genet. 2014 May 8;10(5):e1004348. doi: 10.1371/journal.pgen.1004348. eCollection 2014 May. PLoS Genet. 2014. PMID: 24809345 Free PMC article.
The UPs and DOWNs of MITF in melanoma resistance.
Kim H, Ronai ZA. Kim H, et al. Pigment Cell Melanoma Res. 2015 Mar;28(2):132-3. doi: 10.1111/pcmr.12338. Epub 2014 Dec 23. Pigment Cell Melanoma Res. 2015. PMID: 25476804 No abstract available.
Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies.
Jeon YJ, Khelifa S, Ratnikov B, Scott DA, Feng Y, Parisi F, Ruller C, Lau E, Kim H, Brill LM, Jiang T, Rimm DL, Cardiff RD, Mills GB, Smith JW, Osterman AL, Kluger Y, Ronai ZA. Jeon YJ, et al. Among authors: kim h. Cancer Cell. 2015 Mar 9;27(3):354-69. doi: 10.1016/j.ccell.2015.02.006. Cancer Cell. 2015. PMID: 25759021 Free PMC article.
SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex.
Feng Y, Pinkerton AB, Hulea L, Zhang T, Davies MA, Grotegut S, Cheli Y, Yin H, Lau E, Kim H, De SK, Barile E, Pellecchia M, Bosenberg M, Li JL, James B, Hassig CA, Brown KM, Topisirovic I, Ronai ZA. Feng Y, et al. Among authors: kim h. Cancer Res. 2015 Dec 15;75(24):5211-8. doi: 10.1158/0008-5472.CAN-15-0885. Epub 2015 Nov 24. Cancer Res. 2015. PMID: 26603897 Free PMC article.
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