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Page 1
Pharmacophore Model for Wnt/Porcupine Inhibitors and Its Use in Drug Design.
Poulsen A, Ho SY, Wang W, Alam J, Jeyaraj DA, Ang SH, Tan ES, Lin GR, Cheong VW, Ke Z, Lee MA, Keller TH. Poulsen A, et al. Among authors: tan es. J Chem Inf Model. 2015 Jul 27;55(7):1435-48. doi: 10.1021/acs.jcim.5b00159. Epub 2015 Jun 15. J Chem Inf Model. 2015. PMID: 26024410
Discovery and Optimization of a Porcupine Inhibitor.
Duraiswamy AJ, Lee MA, Madan B, Ang SH, Tan ES, Cheong WW, Ke Z, Pendharkar V, Ding LJ, Chew YS, Manoharan V, Sangthongpitag K, Alam J, Poulsen A, Ho SY, Virshup DM, Keller TH. Duraiswamy AJ, et al. Among authors: tan es. J Med Chem. 2015 Aug 13;58(15):5889-99. doi: 10.1021/acs.jmedchem.5b00507. Epub 2015 Jul 16. J Med Chem. 2015. PMID: 26110200
Scaffold Hopping and Optimization of Maleimide Based Porcupine Inhibitors.
Ho SY, Alam J, Jeyaraj DA, Wang W, Lin GR, Ang SH, Tan ESW, Lee MA, Ke Z, Madan B, Virshup DM, Ding LJ, Manoharan V, Chew YS, Low CB, Pendharkar V, Sangthongpitag K, Hill J, Keller TH, Poulsen A. Ho SY, et al. J Med Chem. 2017 Aug 10;60(15):6678-6692. doi: 10.1021/acs.jmedchem.7b00662. Epub 2017 Jul 20. J Med Chem. 2017. PMID: 28671458
Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors.
Kwiatkowski J, Liu B, Tee DHY, Chen G, Ahmad NHB, Wong YX, Poh ZY, Ang SH, Tan ESW, Ong EH, Nurul Dinie, Poulsen A, Pendharkar V, Sangthongpitag K, Lee MA, Sepramaniam S, Ho SY, Cherian J, Hill J, Keller TH, Hung AW. Kwiatkowski J, et al. J Med Chem. 2018 May 24;61(10):4386-4396. doi: 10.1021/acs.jmedchem.8b00060. Epub 2018 May 4. J Med Chem. 2018. PMID: 29688013
Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia.
Yang H, Chennamaneni LR, Ho MWT, Ang SH, Tan ESW, Jeyaraj DA, Yeap YS, Liu B, Ong EH, Joy JK, Wee JLK, Kwek P, Retna P, Dinie N, Nguyen TTH, Tai SJ, Manoharan V, Pendharkar V, Low CB, Chew YS, Vuddagiri S, Sangthongpitag K, Choong ML, Lee MA, Kannan S, Verma CS, Poulsen A, Lim S, Chuah C, Ong TS, Hill J, Matter A, Nacro K. Yang H, et al. J Med Chem. 2018 May 24;61(10):4348-4369. doi: 10.1021/acs.jmedchem.7b01714. Epub 2018 May 7. J Med Chem. 2018. PMID: 29683667
Accelerating access to human genomics for public health: perspectives from the Western Pacific region.
Expert Meeting on Accelerating Access to Human Genomics for Public Health Participants. Expert Meeting on Accelerating Access to Human Genomics for Public Health Participants. Lancet Reg Health West Pac. 2024 Dec 10;53:101265. doi: 10.1016/j.lanwpc.2024.101265. eCollection 2024 Dec. Lancet Reg Health West Pac. 2024. PMID: 39759797 Free PMC article. No abstract available.
Advancing precision medicine through the integration of clinical cardiovascular genetics - An Asian perspective.
Balakrishnan ID, Bylstra Y, Fong N, Chai NBS, Kam S, Khoo CY, Chan LLH, Koh AS, Tang HC, Lim E, Tan JL, Lim WK, Pua CJ, Sim D, Cook SA, Tan ES, Yeo KK, Jamuar SS. Balakrishnan ID, et al. Among authors: tan es. Genet Med Open. 2024 Jul 24;2:101877. doi: 10.1016/j.gimo.2024.101877. eCollection 2024. Genet Med Open. 2024. PMID: 39669619 Free PMC article.
Clinical Implementation of Nephrologist-Led Genomic Testing for Glomerular Diseases in Singapore: Rationale and Protocol.
Lim C, Lim RS, Choo J, Leow EH, Chan GC, Zhang Y, Ng JL, Chin HL, Tan ES, Goh J, Gandhi N, Ng YH, Than M, Ganesan I, Chong SL, Yap C, Chao SM, Cham B, Kam S, Lim JY, Mok I, Tan HZ, Kwek JL, Lee TL, Wang Z, Goh SM, Lim R, Yeo SC, Teo BW, Da Y, Matchar D, Ng KH. Lim C, et al. Among authors: tan es. Am J Nephrol. 2024 Dec 3:1-14. doi: 10.1159/000542942. Online ahead of print. Am J Nephrol. 2024. PMID: 39626636 Free article.
298 results