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Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.
Duffy BC, Liu S, Martin GS, Wang R, Hsia MM, Zhao H, Guo C, Ellis M, Quinn JF, Kharenko OA, Norek K, Gesner EM, Young PR, McLure KG, Wagner GS, Lakshminarasimhan D, White A, Suto RK, Hansen HC, Kitchen DB. Duffy BC, et al. Among authors: zhao h. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2818-23. doi: 10.1016/j.bmcl.2015.04.107. Epub 2015 May 11. Bioorg Med Chem Lett. 2015. PMID: 26022843
A new class of penicillin-binding protein inhibitors to address drug-resistant Neisseria gonorrhoeae.
Uehara T, Zulli AL, Miller B, Avery LM, Boyd SA, Chatwin CL, Chu GH, Drager AS, Edwards M, Emeigh Hart SG, Myers CL, Rongala G, Stevenson A, Uehara K, Yi F, Wang B, Liu Z, Wang M, Zhao Z, Zhou X, Zhao H, Stratton CM, Bala S, Davies C, Tkavc R, Jerse AE, Pevear DC, Burns CJ, Daigle DM, Condon SM. Uehara T, et al. Among authors: zhao h. bioRxiv [Preprint]. 2024 Dec 27:2024.12.27.630553. doi: 10.1101/2024.12.27.630553. bioRxiv. 2024. PMID: 39763734 Free PMC article. Preprint.
Glecirasib in KRASG12C-mutated nonsmall-cell lung cancer: a phase 2b trial.
Shi Y, Fang J, Xing L, Yao Y, Zhang J, Liu L, Wang Y, Hu C, Xiong J, Liu Z, Yang R, Wang Z, Zhao E, Wang M, Zhao Y, Tang K, Li Z, Song Z, Li Y, Zhuang W, Jin B, Cheng Y, Hu Y, Gu Y, Wu L, Ma R, Yu Q, Yu Y, Zhao J, Zhao H, Lv D, Shang Y, Xing P, Zhou J, Li X, Liu Z, Dai Z, Xia G, Chen X, Ba Y, Bai C, Li Q, An G, Hu W, Wang Y, Wang-Gillam A, Ding Y, Li Q, Rao Z. Shi Y, et al. Among authors: zhao h. Nat Med. 2025 Jan 6. doi: 10.1038/s41591-024-03401-z. Online ahead of print. Nat Med. 2025. PMID: 39762419
Increased in vitro antimicrobial resistance of Mycoplasma pneumoniae isolates obtained from children in Beijing, China, in 2023.
Jia X, Chen Y, Gao Y, Ren X, Du B, Zhao H, Feng Y, Xue G, Cui J, Gan L, Feng J, Fan Z, Fu T, Xu Z, Yu Z, Yang Y, Zhao S, Huang L, Ke Y, Liu C, Yan C, Yuan J. Jia X, et al. Among authors: zhao h. Front Cell Infect Microbiol. 2024 Dec 20;14:1478087. doi: 10.3389/fcimb.2024.1478087. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 39760095 Free PMC article.
36,683 results
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