Seiffert D - Search Results

1

In vitro pharmacological characterization of vorapaxar, a novel platelet thrombin receptor antagonist.

Hawes BE, Zhai Y, Hesk D, Wirth M, Wei H, Chintala M, Seiffert D. Hawes BE, et al. Among authors: seiffert d. Eur J Pharmacol. 2015 Sep 5;762:221-8. doi: 10.1016/j.ejphar.2015.05.046. Epub 2015 May 27. Eur J Pharmacol. 2015. PMID: 26022529

2

Platelet transfusion reverses bleeding evoked by triple anti-platelet therapy including vorapaxar, a novel platelet thrombin receptor antagonist.

Cai TQ, Wickham LA, Sitko G, Michener MS, Raubertas R, Handt L, Chintala M, Seiffert D, Forrest M. Cai TQ, et al. Among authors: seiffert d. Eur J Pharmacol. 2015 Jul 5;758:107-14. doi: 10.1016/j.ejphar.2015.03.073. Epub 2015 Apr 7. Eur J Pharmacol. 2015. PMID: 25857224

3

Inhibition of Factor XI activity as a promising antithrombotic strategy.

Chen Z, Seiffert D, Hawes B. Chen Z, et al. Among authors: seiffert d. Drug Discov Today. 2014 Sep;19(9):1435-9. doi: 10.1016/j.drudis.2014.04.018. Epub 2014 May 2. Drug Discov Today. 2014. PMID: 24794465 Review.

4

Platelet function recovery following exposure to triple anti-platelet inhibitors using an in vitro transfusion model.

Bhal V, Herr MJ, Dixon M, Akins S, Hord E, White MM, Seiffert D, Kotha J, Jennings LK. Bhal V, et al. Among authors: seiffert d. Thromb Res. 2015 Dec;136(6):1216-23. doi: 10.1016/j.thromres.2015.09.009. Epub 2015 Sep 11. Thromb Res. 2015. PMID: 26412559

5

Factor XIIa as a Novel Target for Thrombosis: Target Engagement Requirement and Efficacy in a Rabbit Model of Microembolic Signals.

Barbieri CM, Wang X, Wu W, Zhou X, Ogawa AM, O'Neill K, Chu D, Castriota G, Seiffert DA, Gutstein DE, Chen Z. Barbieri CM, et al. Among authors: seiffert da. J Pharmacol Exp Ther. 2017 Mar;360(3):466-475. doi: 10.1124/jpet.116.238493. Epub 2016 Dec 29. J Pharmacol Exp Ther. 2017. PMID: 28035006

6

Challenges and promises of developing thrombin receptor antagonists.

Yang J, Xu K, Seiffert D. Yang J, et al. Among authors: seiffert d. Recent Pat Cardiovasc Drug Discov. 2010 Nov;5(3):162-70. doi: 10.2174/157489010793351980. Recent Pat Cardiovasc Drug Discov. 2010. PMID: 20874673 Review.

7

An optimized agonist peptide of protease-activated receptor 4 and its use in a validated platelet-aggregation assay.

Yang J, Mapelli C, Wang Z, Sum CS, Hua J, Lawrence RM, Ni Y, Seiffert DA. Yang J, et al. Platelets. 2022 Oct 3;33(7):979-986. doi: 10.1080/09537104.2022.2053091. Epub 2022 Mar 28. Platelets. 2022. PMID: 35343875 Free article.

8

Factor XIIa inhibition by Infestin-4: in vitro mode of action and in vivo antithrombotic benefit.

Xu Y, Cai TQ, Castriota G, Zhou Y, Hoos L, Jochnowitz N, Loewrigkeit C, Cook JA, Wickham A, Metzger JM, Ogletree ML, Seiffert DA, Chen Z. Xu Y, et al. Thromb Haemost. 2014 Apr 1;111(4):694-704. doi: 10.1160/TH13-08-0668. Epub 2013 Dec 12. Thromb Haemost. 2014. PMID: 24336918

9

Differential effect of the GPIIb/IIIa antagonist orbofiban on human platelet aggregate formation in vitro.

Racanelli AL, Gibbs SK, Zondlo SC, Seiffert DA, Friedman SM, Feuerstein GZ. Racanelli AL, et al. Thromb Res. 2003 May 1;110(2-3):99-105. doi: 10.1016/s0049-3848(03)00337-2. Thromb Res. 2003. PMID: 12893024

10

Apixaban Inhibits Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits.

Zhou X, Wu W, Chu L, Gutstein DE, Seiffert D, Wang X. Zhou X, et al. Among authors: seiffert d. J Pharmacol Exp Ther. 2016 Sep;358(3):405-12. doi: 10.1124/jpet.116.234575. Epub 2016 Jul 6. J Pharmacol Exp Ther. 2016. PMID: 27384071

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