Wajant H - Search Results

1

Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GVHD.

Chopra M, Brandl A, Siegmund D, Mottok A, Schäfer V, Biehl M, Kraus S, Bäuerlein CA, Ritz M, Mattenheimer K, Schwinn S, Seher A, Grabinger T, Einsele H, Rosenwald A, Brunner T, Beilhack A, Wajant H. Chopra M, et al. Among authors: wajant h. Blood. 2015 Jul 23;126(4):437-44. doi: 10.1182/blood-2015-01-620583. Epub 2015 May 26. Blood. 2015. PMID: 26012567 Free PMC article.

2

p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells.

Bartke T, Siegmund D, Peters N, Reichwein M, Henkler F, Scheurich P, Wajant H. Bartke T, et al. Among authors: wajant h. Oncogene. 2001 Feb 1;20(5):571-80. doi: 10.1038/sj.onc.1204124. Oncogene. 2001. PMID: 11313989

3

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.

Kreuz S, Siegmund D, Scheurich P, Wajant H. Kreuz S, et al. Among authors: wajant h. Mol Cell Biol. 2001 Jun;21(12):3964-73. doi: 10.1128/MCB.21.12.3964-3973.2001. Mol Cell Biol. 2001. PMID: 11359904 Free PMC article.

4

Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway.

Siegmund D, Mauri D, Peters N, Juo P, Thome M, Reichwein M, Blenis J, Scheurich P, Tschopp J, Wajant H. Siegmund D, et al. Among authors: wajant h. J Biol Chem. 2001 Aug 31;276(35):32585-90. doi: 10.1074/jbc.M100444200. Epub 2001 May 30. J Biol Chem. 2001. PMID: 11384965 Free article.

5

Tumor necrosis factor (TNF) and phorbol ester induce TNF-related apoptosis-inducing ligand (TRAIL) under critical involvement of NF-kappa B essential modulator (NEMO)/IKKgamma.

Siegmund D, Hausser A, Peters N, Scheurich P, Wajant H. Siegmund D, et al. Among authors: wajant h. J Biol Chem. 2001 Nov 23;276(47):43708-12. doi: 10.1074/jbc.M106421200. Epub 2001 Sep 13. J Biol Chem. 2001. PMID: 11557763 Free article.

6

Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis.

Weingärtner M, Siegmund D, Schlecht U, Fotin-Mleczek M, Scheurich P, Wajant H. Weingärtner M, et al. Among authors: wajant h. J Biol Chem. 2002 Sep 20;277(38):34853-9. doi: 10.1074/jbc.M205149200. Epub 2002 Jul 8. J Biol Chem. 2002. PMID: 12105203 Free article.

7

Rocaglamide derivatives are potent inhibitors of NF-kappa B activation in T-cells.

Baumann B, Bohnenstengel F, Siegmund D, Wajant H, Weber C, Herr I, Debatin KM, Proksch P, Wirth T. Baumann B, et al. Among authors: wajant h. J Biol Chem. 2002 Nov 22;277(47):44791-800. doi: 10.1074/jbc.M208003200. Epub 2002 Sep 16. J Biol Chem. 2002. PMID: 12237314 Free article.

8

Intracellular localization and transcriptional regulation of tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4).

Glauner H, Siegmund D, Motejadded H, Scheurich P, Henkler F, Janssen O, Wajant H. Glauner H, et al. Among authors: wajant h. Eur J Biochem. 2002 Oct;269(19):4819-29. doi: 10.1046/j.1432-1033.2002.03180.x. Eur J Biochem. 2002. PMID: 12354113 Free article.

9

Selective inhibition of FLICE-like inhibitory protein expression with small interfering RNA oligonucleotides is sufficient to sensitize tumor cells for TRAIL-induced apoptosis.

Siegmund D, Hadwiger P, Pfizenmaier K, Vornlocher HP, Wajant H. Siegmund D, et al. Among authors: wajant h. Mol Med. 2002 Nov;8(11):725-32. Mol Med. 2002. PMID: 12520089 Free PMC article.

10

NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP.

Kreuz S, Siegmund D, Rumpf JJ, Samel D, Leverkus M, Janssen O, Häcker G, Dittrich-Breiholz O, Kracht M, Scheurich P, Wajant H. Kreuz S, et al. Among authors: wajant h. J Cell Biol. 2004 Aug 2;166(3):369-80. doi: 10.1083/jcb.200401036. J Cell Biol. 2004. PMID: 15289496 Free PMC article.

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