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212 results

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Page 1
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.
Chen HJ, Sun J, Huang Z, Hou H Jr, Arcilla M, Rakhilin N, Joe DJ, Choi J, Gadamsetty P, Milsom J, Nandakumar G, Longman R, Zhou XK, Edwards R, Chen J, Chen KY, Bu P, Wang L, Xu Y, Munroe R, Abratte C, Miller AD, Gümüş ZH, Shuler M, Nishimura N, Edelmann W, Shen X, Lipkin SM. Chen HJ, et al. Among authors: longman r. Nat Biotechnol. 2015 Jun;33(6):656-60. doi: 10.1038/nbt.3239. Epub 2015 May 25. Nat Biotechnol. 2015. PMID: 26006007 Free PMC article.
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis.
Viladomiu M, Khounlotham M, Dogan B, Lima SF, Elsaadi A, Cardakli E, Castellanos JG, Ng C, Herzog J, Schoenborn AA, Ellermann M, Liu B, Zhang S, Gulati AS, Sartor RB, Simpson KW, Lipkin SM, Longman RS. Viladomiu M, et al. Among authors: longman rs. Cell Rep. 2022 Nov 15;41(7):111637. doi: 10.1016/j.celrep.2022.111637. Cell Rep. 2022. PMID: 36384110 Free PMC article.
Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation.
Arifuzzaman M, Won TH, Li TT, Yano H, Digumarthi S, Heras AF, Zhang W, Parkhurst CN, Kashyap S, Jin WB, Putzel GG, Tsou AM, Chu C, Wei Q, Grier A; JRI IBD Live Cell Bank Consortium; Worgall S, Guo CJ, Schroeder FC, Artis D. Arifuzzaman M, et al. Nature. 2022 Nov;611(7936):578-584. doi: 10.1038/s41586-022-05380-y. Epub 2022 Nov 2. Nature. 2022. PMID: 36323778 Free PMC article.
Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces.
Tsou AM, Yano H, Parkhurst CN, Mahlakõiv T, Chu C, Zhang W, He Z, Jarick KJ, Zhong C, Putzel GG, Hatazaki M; JRI IBD Live Cell Bank Consortium; Lorenz IC, Andrew D, Balderes P, Klose CSN, Lira SA, Artis D. Tsou AM, et al. Nature. 2022 Nov;611(7937):787-793. doi: 10.1038/s41586-022-05297-6. Epub 2022 Nov 2. Nature. 2022. PMID: 36323781 Free PMC article.
Bile acid metabolites control TH17 and Treg cell differentiation.
Hang S, Paik D, Yao L, Kim E, Trinath J, Lu J, Ha S, Nelson BN, Kelly SP, Wu L, Zheng Y, Longman RS, Rastinejad F, Devlin AS, Krout MR, Fischbach MA, Littman DR, Huh JR. Hang S, et al. Among authors: longman rs. Nature. 2019 Dec;576(7785):143-148. doi: 10.1038/s41586-019-1785-z. Epub 2019 Nov 27. Nature. 2019. PMID: 31776512 Free PMC article.
Human gut bacteria produce ΤΗ17-modulating bile acid metabolites.
Paik D, Yao L, Zhang Y, Bae S, D'Agostino GD, Zhang M, Kim E, Franzosa EA, Avila-Pacheco J, Bisanz JE, Rakowski CK, Vlamakis H, Xavier RJ, Turnbaugh PJ, Longman RS, Krout MR, Clish CB, Rastinejad F, Huttenhower C, Huh JR, Devlin AS. Paik D, et al. Among authors: longman rs. Nature. 2022 Mar;603(7903):907-912. doi: 10.1038/s41586-022-04480-z. Epub 2022 Mar 16. Nature. 2022. PMID: 35296854 Free PMC article.
ZBTB46 defines and regulates ILC3s that protect the intestine.
Zhou W, Zhou L, Zhou J; JRI Live Cell Bank; Chu C, Zhang C, Sockolow RE, Eberl G, Sonnenberg GF. Zhou W, et al. Nature. 2022 Sep;609(7925):159-165. doi: 10.1038/s41586-022-04934-4. Epub 2022 Jul 13. Nature. 2022. PMID: 35831503 Free PMC article.
ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut.
Lyu M, Suzuki H, Kang L, Gaspal F, Zhou W, Goc J, Zhou L, Zhou J, Zhang W; JRI Live Cell Bank; Shen Z, Fox JG, Sockolow RE, Laufer TM, Fan Y, Eberl G, Withers DR, Sonnenberg GF. Lyu M, et al. Nature. 2022 Oct;610(7933):744-751. doi: 10.1038/s41586-022-05141-x. Epub 2022 Sep 7. Nature. 2022. PMID: 36071169 Free PMC article.
CTLA-4-expressing ILC3s restrain interleukin-23-mediated inflammation.
Ahmed A, Joseph AM, Zhou J, Horn V, Uddin J, Lyu M, Goc J; JRI Live Cell Bank; Sockolow RE, Wing JB, Vivier E, Sakaguchi S, Sonnenberg GF. Ahmed A, et al. Nature. 2024 Jun;630(8018):976-983. doi: 10.1038/s41586-024-07537-3. Epub 2024 Jun 12. Nature. 2024. PMID: 38867048 Free PMC article.
212 results