Patel SS - Search Results

1

Cooperative base pair melting by helicase and polymerase positioned one nucleotide from each other.

Nandakumar D, Pandey M, Patel SS. Nandakumar D, et al. Among authors: patel ss. Elife. 2015 May 13;4:e06562. doi: 10.7554/eLife.06562. Elife. 2015. PMID: 25970034 Free PMC article.

2

A ring-opening mechanism for DNA binding in the central channel of the T7 helicase-primase protein.

Ahnert P, Picha KM, Patel SS. Ahnert P, et al. Among authors: patel ss. EMBO J. 2000 Jul 3;19(13):3418-27. doi: 10.1093/emboj/19.13.3418. EMBO J. 2000. PMID: 10880454 Free PMC article.

3

The intercalating beta-hairpin of T7 RNA polymerase plays a role in promoter DNA melting and in stabilizing the melted DNA for efficient RNA synthesis.

Stano NM, Patel SS. Stano NM, et al. Among authors: patel ss. J Mol Biol. 2002 Feb 1;315(5):1009-25. doi: 10.1006/jmbi.2001.5313. J Mol Biol. 2002. PMID: 11827472

4

T7 DNA helicase: a molecular motor that processively and unidirectionally translocates along single-stranded DNA.

Kim DE, Narayan M, Patel SS. Kim DE, et al. Among authors: patel ss. J Mol Biol. 2002 Aug 30;321(5):807-19. doi: 10.1016/s0022-2836(02)00733-7. J Mol Biol. 2002. PMID: 12206763

5

The DNA-unwinding mechanism of the ring helicase of bacteriophage T7.

Jeong YJ, Levin MK, Patel SS. Jeong YJ, et al. Among authors: patel ss. Proc Natl Acad Sci U S A. 2004 May 11;101(19):7264-9. doi: 10.1073/pnas.0400372101. Epub 2004 May 3. Proc Natl Acad Sci U S A. 2004. PMID: 15123793 Free PMC article.

6

Insights into the role of an active site aspartate in Ty1 reverse transcriptase polymerization.

Pandey M, Patel S, Gabriel A. Pandey M, et al. J Biol Chem. 2004 Nov 12;279(46):47840-8. doi: 10.1074/jbc.M406019200. Epub 2004 Aug 28. J Biol Chem. 2004. PMID: 15333632 Free article.

7

A Brownian motor mechanism of translocation and strand separation by hepatitis C virus helicase.

Levin MK, Gurjar M, Patel SS. Levin MK, et al. Among authors: patel ss. Nat Struct Mol Biol. 2005 May;12(5):429-35. doi: 10.1038/nsmb920. Epub 2005 Apr 3. Nat Struct Mol Biol. 2005. PMID: 15806107

8

DNA synthesis provides the driving force to accelerate DNA unwinding by a helicase.

Stano NM, Jeong YJ, Donmez I, Tummalapalli P, Levin MK, Patel SS. Stano NM, et al. Among authors: patel ss. Nature. 2005 May 19;435(7040):370-3. doi: 10.1038/nature03615. Nature. 2005. PMID: 15902262 Free PMC article.

9

T7 RNA polymerase-induced bending of promoter DNA is coupled to DNA opening.

Tang GQ, Patel SS. Tang GQ, et al. Among authors: patel ss. Biochemistry. 2006 Apr 18;45(15):4936-46. doi: 10.1021/bi0522910. Biochemistry. 2006. PMID: 16605261

10

Rapid binding of T7 RNA polymerase is followed by simultaneous bending and opening of the promoter DNA.

Tang GQ, Patel SS. Tang GQ, et al. Among authors: patel ss. Biochemistry. 2006 Apr 18;45(15):4947-56. doi: 10.1021/bi052292s. Biochemistry. 2006. PMID: 16605262

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