Ojima I - Search Results

1

New Monocyclic, Bicyclic, and Tricyclic Ethynylcyanodienones as Activators of the Keap1/Nrf2/ARE Pathway and Inhibitors of Inducible Nitric Oxide Synthase.

Li W, Zheng S, Higgins M, Morra RP Jr, Mendis AT, Chien CW, Ojima I, Mierke DF, Dinkova-Kostova AT, Honda T. Li W, et al. Among authors: ojima i. J Med Chem. 2015 Jun 11;58(11):4738-48. doi: 10.1021/acs.jmedchem.5b00393. Epub 2015 May 20. J Med Chem. 2015. PMID: 25965897

2

Synthesis and structure-activity relationships of new antitumor taxoids. Effects of cyclohexyl substitution at the C-3' and/or C-2 of taxotere (docetaxel).

Ojima I, Duclos O, Zucco M, Bissery MC, Combeau C, Vrignaud P, Riou JF, Lavelle F. Ojima I, et al. J Med Chem. 1994 Aug 5;37(16):2602-8. doi: 10.1021/jm00042a013. J Med Chem. 1994. PMID: 7914541

3

Structure-activity relationships of new taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III.

Ojima I, Park YH, Sun CM, Fenoglio I, Appendino G, Pera P, Bernacki RJ. Ojima I, et al. J Med Chem. 1994 May 13;37(10):1408-10. doi: 10.1021/jm00036a004. J Med Chem. 1994. PMID: 8182698 No abstract available.

4

Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells.

Ojima I, Slater JC, Michaud E, Kuduk SD, Bounaud PY, Vrignaud P, Bissery MC, Veith JM, Pera P, Bernacki RJ. Ojima I, et al. J Med Chem. 1996 Sep 27;39(20):3889-96. doi: 10.1021/jm9604080. J Med Chem. 1996. PMID: 8831755

5

Syntheses and structure-activity relationships of taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III.

Ojima I, Slater JC, Kuduk SD, Takeuchi CS, Gimi RH, Sun CM, Park YH, Pera P, Veith JM, Bernacki RJ. Ojima I, et al. J Med Chem. 1997 Jan 31;40(3):267-78. doi: 10.1021/jm960563e. J Med Chem. 1997. PMID: 9022793

6

Synthesis and structure-activity relationships of nonaromatic taxoids: effects of alkyl and alkenyl ester groups on cytotoxicity.

Ojima I, Kuduk SD, Pera P, Veith JM, Bernacki RJ. Ojima I, et al. J Med Chem. 1997 Jan 31;40(3):279-85. doi: 10.1021/jm9606711. J Med Chem. 1997. PMID: 9022794

7

New taxanes as highly efficient reversal agents for multidrug resistance in cancer cells.

Ojima I, Bounaud PY, Takeuchi C, Pera P, Bernacki RJ. Ojima I, et al. Bioorg Med Chem Lett. 1998 Jan 20;8(2):189-94. doi: 10.1016/s0960-894x(97)10218-9. Bioorg Med Chem Lett. 1998. PMID: 9871652

8

New photoaffinity analogs of paclitaxel.

Ojima I, Bounaud PY, Ahern DG. Ojima I, et al. Bioorg Med Chem Lett. 1999 Apr 19;9(8):1189-94. doi: 10.1016/s0960-894x(99)00161-4. Bioorg Med Chem Lett. 1999. PMID: 10328311

9

Synthesis and structure-activity relationships of new second-generation taxoids.

Ojima I, Wang T, Miller ML, Lin S, Borella CP, Geng X, Pera P, Bernacki RJ. Ojima I, et al. Bioorg Med Chem Lett. 1999 Dec 20;9(24):3423-8. doi: 10.1016/s0960-894x(99)00629-0. Bioorg Med Chem Lett. 1999. PMID: 10617084

10

Structure-activity relationship study of taxoids for their ability to activate murine macrophages as well as inhibit the growth of macrophage-like cells.

Ojima I, Fumero-Oderda CL, Kuduk SD, Ma Z, Kirikae F, Kirikae T. Ojima I, et al. Bioorg Med Chem. 2003 Jul 3;11(13):2867-88. doi: 10.1016/s0968-0896(03)00181-0. Bioorg Med Chem. 2003. PMID: 12788358

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