Kwan R - Search Results

1

Human keratin 8 variants promote mouse acetaminophen hepatotoxicity coupled with c-jun amino-terminal kinase activation and protein adduct formation.

Guldiken N, Zhou Q, Kucukoglu O, Rehm M, Levada K, Gross A, Kwan R, James LP, Trautwein C, Omary MB, Strnad P. Guldiken N, et al. Among authors: kwan r. Hepatology. 2015 Sep;62(3):876-86. doi: 10.1002/hep.27891. Epub 2015 Jul 3. Hepatology. 2015. PMID: 25963979 Free PMC article.

2

Panhematin provides a therapeutic benefit in experimental pancreatitis.

Habtezion A, Kwan R, Akhtar E, Wanaski SP, Collins SD, Wong RJ, Stevenson DK, Butcher EC, Omary MB. Habtezion A, et al. Among authors: kwan r. Gut. 2011 May;60(5):671-9. doi: 10.1136/gut.2010.217208. Epub 2010 Dec 15. Gut. 2011. PMID: 21159893 Free PMC article.

3

Keratin 8 phosphorylation regulates its transamidation and hepatocyte Mallory-Denk body formation.

Kwan R, Hanada S, Harada M, Strnad P, Li DH, Omary MB. Kwan R, et al. FASEB J. 2012 Jun;26(6):2318-26. doi: 10.1096/fj.11-198580. Epub 2012 Feb 23. FASEB J. 2012. PMID: 22362895 Free PMC article.

4

Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation.

Snider NT, Leonard JM, Kwan R, Griggs NW, Rui L, Omary MB. Snider NT, et al. Among authors: kwan r. J Cell Biol. 2013 Feb 4;200(3):241-7. doi: 10.1083/jcb.201209028. Epub 2013 Jan 28. J Cell Biol. 2013. PMID: 23358244 Free PMC article.

5

Lamin aggregation is an early sensor of porphyria-induced liver injury.

Singla A, Griggs NW, Kwan R, Snider NT, Maitra D, Ernst SA, Herrmann H, Omary MB. Singla A, et al. Among authors: kwan r. J Cell Sci. 2013 Jul 15;126(Pt 14):3105-12. doi: 10.1242/jcs.123026. Epub 2013 May 2. J Cell Sci. 2013. PMID: 23641075 Free PMC article.

6

Mutation of caspase-digestion sites in keratin 18 interferes with filament reorganization, and predisposes to hepatocyte necrosis and loss of membrane integrity.

Weerasinghe SV, Ku NO, Altshuler PJ, Kwan R, Omary MB. Weerasinghe SV, et al. Among authors: kwan r. J Cell Sci. 2014 Apr 1;127(Pt 7):1464-75. doi: 10.1242/jcs.138479. Epub 2014 Jan 24. J Cell Sci. 2014. PMID: 24463813 Free PMC article.

7

Absence of keratins 8 and 18 in rodent epithelial cell lines associates with keratin gene mutation and DNA methylation: Cell line selective effects on cell invasion.

Kwan R, Looi KS, Omary MB. Kwan R, et al. Exp Cell Res. 2015 Jul 1;335(1):12-22. doi: 10.1016/j.yexcr.2015.04.003. Epub 2015 Apr 14. Exp Cell Res. 2015. PMID: 25882495 Free PMC article.

8

PKC412 normalizes mutation-related keratin filament disruption and hepatic injury in mice by promoting keratin-myosin binding.

Kwan R, Chen L, Looi K, Tao GZ, Weerasinghe SV, Snider NT, Conti MA, Adelstein RS, Xie Q, Omary MB. Kwan R, et al. Hepatology. 2015 Dec;62(6):1858-69. doi: 10.1002/hep.27965. Epub 2015 Aug 25. Hepatology. 2015. PMID: 26126491 Free PMC article.

9

Absence of keratin 8 or 18 promotes antimitochondrial autoantibody formation in aging male mice.

Toivola DM, Habtezion A, Misiorek JO, Zhang L, Nyström JH, Sharpe O, Robinson WH, Kwan R, Omary MB. Toivola DM, et al. Among authors: kwan r. FASEB J. 2015 Dec;29(12):5081-9. doi: 10.1096/fj.14-269795. Epub 2015 Sep 23. FASEB J. 2015. PMID: 26399787 Free PMC article.

10

Clusterin and Pycr1 alterations associate with strain and model differences in susceptibility to experimental pancreatitis.

Iyer S, Park MJ, Moons D, Kwan R, Liao J, Liu L, Omary MB. Iyer S, et al. Among authors: kwan r. Biochem Biophys Res Commun. 2017 Jan 22;482(4):1346-1352. doi: 10.1016/j.bbrc.2016.12.039. Epub 2016 Dec 7. Biochem Biophys Res Commun. 2017. PMID: 27939882 Free PMC article.

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