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Genome editing technologies: defining a path to clinic.
Corrigan-Curay J, O'Reilly M, Kohn DB, Cannon PM, Bao G, Bushman FD, Carroll D, Cathomen T, Joung JK, Roth D, Sadelain M, Scharenberg AM, von Kalle C, Zhang F, Jambou R, Rosenthal E, Hassani M, Singh A, Porteus MH. Corrigan-Curay J, et al. Among authors: scharenberg am. Mol Ther. 2015 May;23(5):796-806. doi: 10.1038/mt.2015.54. Mol Ther. 2015. PMID: 25943494 Free PMC article. No abstract available.
Ethical and regulatory aspects of genome editing.
Kohn DB, Porteus MH, Scharenberg AM. Kohn DB, et al. Among authors: scharenberg am. Blood. 2016 May 26;127(21):2553-60. doi: 10.1182/blood-2016-01-678136. Epub 2016 Apr 6. Blood. 2016. PMID: 27053531 Free article. Review.
Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases.
Osborn MJ, Webber BR, Knipping F, Lonetree CL, Tennis N, DeFeo AP, McElroy AN, Starker CG, Lee C, Merkel S, Lund TC, Kelly-Spratt KS, Jensen MC, Voytas DF, von Kalle C, Schmidt M, Gabriel R, Hippen KL, Miller JS, Scharenberg AM, Tolar J, Blazar BR. Osborn MJ, et al. Among authors: scharenberg am. Mol Ther. 2016 Mar;24(3):570-81. doi: 10.1038/mt.2015.197. Epub 2015 Oct 27. Mol Ther. 2016. PMID: 26502778 Free PMC article.
Tracking genome engineering outcome at individual DNA breakpoints.
Certo MT, Ryu BY, Annis JE, Garibov M, Jarjour J, Rawlings DJ, Scharenberg AM. Certo MT, et al. Among authors: scharenberg am. Nat Methods. 2011 Jul 10;8(8):671-6. doi: 10.1038/nmeth.1648. Nat Methods. 2011. PMID: 21743461 Free PMC article.
Engineering HIV-Resistant, Anti-HIV Chimeric Antigen Receptor T Cells.
Hale M, Mesojednik T, Romano Ibarra GS, Sahni J, Bernard A, Sommer K, Scharenberg AM, Rawlings DJ, Wagner TA. Hale M, et al. Among authors: scharenberg am. Mol Ther. 2017 Mar 1;25(3):570-579. doi: 10.1016/j.ymthe.2016.12.023. Epub 2017 Jan 28. Mol Ther. 2017. PMID: 28143740 Free PMC article.
124 results