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Genome editing technologies: defining a path to clinic.
Corrigan-Curay J, O'Reilly M, Kohn DB, Cannon PM, Bao G, Bushman FD, Carroll D, Cathomen T, Joung JK, Roth D, Sadelain M, Scharenberg AM, von Kalle C, Zhang F, Jambou R, Rosenthal E, Hassani M, Singh A, Porteus MH. Corrigan-Curay J, et al. Among authors: cathomen t. Mol Ther. 2015 May;23(5):796-806. doi: 10.1038/mt.2015.54. Mol Ther. 2015. PMID: 25943494 Free PMC article. No abstract available.
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1.
Torella L, Klermund J, Bilbao-Arribas M, Tamayo I, Andrieux G, Chmielewski KO, Vales A, Olagüe C, Moreno-Luqui D, Raimondi I, Abad A, Torrens-Baile J, Salido E, Huarte M, Hernaez M, Boerries M, Cathomen T, Zabaleta N, Gonzalez-Aseguinolaza G. Torella L, et al. Among authors: cathomen t. EMBO Mol Med. 2024 Jan;16(1):112-131. doi: 10.1038/s44321-023-00008-8. Epub 2024 Jan 5. EMBO Mol Med. 2024. PMID: 38182795 Free PMC article.
CRISPR-Cas12a for Highly Efficient and Marker-Free Targeted Integration in Human Pluripotent Stem Cells.
Hammad R, Alzubi J, Rhiel M, Chmielewski KO, Mosti L, Rositzka J, Heugel M, Lawrenz J, Pennucci V, Gläser B, Fischer J, Schambach A, Moritz T, Lachmann N, Cornu TI, Mussolino C, Schäfer R, Cathomen T. Hammad R, et al. Among authors: cathomen t. Int J Mol Sci. 2024 Jan 12;25(2):985. doi: 10.3390/ijms25020985. Int J Mol Sci. 2024. PMID: 38256061 Free PMC article.
Zinc-finger nucleases: the next generation emerges.
Cathomen T, Joung JK. Cathomen T, et al. Mol Ther. 2008 Jul;16(7):1200-7. doi: 10.1038/mt.2008.114. Epub 2008 Jun 10. Mol Ther. 2008. PMID: 18545224 Free article. Review.
Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification.
Maeder ML, Thibodeau-Beganny S, Osiak A, Wright DA, Anthony RM, Eichtinger M, Jiang T, Foley JE, Winfrey RJ, Townsend JA, Unger-Wallace E, Sander JD, Müller-Lerch F, Fu F, Pearlberg J, Göbel C, Dassie JP, Pruett-Miller SM, Porteus MH, Sgroi DC, Iafrate AJ, Dobbs D, McCray PB Jr, Cathomen T, Voytas DF, Joung JK. Maeder ML, et al. Among authors: cathomen t. Mol Cell. 2008 Jul 25;31(2):294-301. doi: 10.1016/j.molcel.2008.06.016. Mol Cell. 2008. PMID: 18657511 Free PMC article.
Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.
Söllü C, Pars K, Cornu TI, Thibodeau-Beganny S, Maeder ML, Joung JK, Heilbronn R, Cathomen T. Söllü C, et al. Among authors: cathomen t. Nucleic Acids Res. 2010 Dec;38(22):8269-76. doi: 10.1093/nar/gkq720. Epub 2010 Aug 16. Nucleic Acids Res. 2010. PMID: 20716517 Free PMC article.
163 results