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Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.
Bednar F, Schofield HK, Collins MA, Yan W, Zhang Y, Shyam N, Eberle JA, Almada LL, Olive KP, Bardeesy N, Fernandez-Zapico ME, Nakada D, Simeone DM, Morrison SJ, Pasca di Magliano M. Bednar F, et al. Among authors: zhang y. Carcinogenesis. 2015 Jul;36(7):730-8. doi: 10.1093/carcin/bgv058. Epub 2015 May 4. Carcinogenesis. 2015. PMID: 25939753 Free PMC article.
Metastatic pancreatic cancer is dependent on oncogenic Kras in mice.
Collins MA, Brisset JC, Zhang Y, Bednar F, Pierre J, Heist KA, Galbán CJ, Galbán S, di Magliano MP. Collins MA, et al. Among authors: zhang y. PLoS One. 2012;7(12):e49707. doi: 10.1371/journal.pone.0049707. Epub 2012 Dec 3. PLoS One. 2012. PMID: 23226501 Free PMC article.
Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation.
Mills LD, Zhang Y, Marler RJ, Herreros-Villanueva M, Zhang L, Almada LL, Couch F, Wetmore C, Pasca di Magliano M, Fernandez-Zapico ME. Mills LD, et al. Among authors: zhang l, zhang y. J Biol Chem. 2013 Apr 26;288(17):11786-94. doi: 10.1074/jbc.M112.438846. Epub 2013 Mar 12. J Biol Chem. 2013. PMID: 23482563 Free PMC article.
Canonical wnt signaling is required for pancreatic carcinogenesis.
Zhang Y, Morris JP 4th, Yan W, Schofield HK, Gurney A, Simeone DM, Millar SE, Hoey T, Hebrok M, Pasca di Magliano M. Zhang Y, et al. Cancer Res. 2013 Aug 1;73(15):4909-22. doi: 10.1158/0008-5472.CAN-12-4384. Epub 2013 Jun 12. Cancer Res. 2013. PMID: 23761328 Free PMC article.
CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice.
Zhang Y, Yan W, Mathew E, Bednar F, Wan S, Collins MA, Evans RA, Welling TH, Vonderheide RH, di Magliano MP. Zhang Y, et al. Cancer Immunol Res. 2014 May;2(5):423-35. doi: 10.1158/2326-6066.CIR-14-0016-T. Epub 2014 Feb 11. Cancer Immunol Res. 2014. PMID: 24795355 Free PMC article.
Immune cells in pancreatic cancer: Joining the dark side.
Zhang Y, McAllister F, Pasca di Magliano M. Zhang Y, et al. Oncoimmunology. 2014 Jun 5;3:e29125. doi: 10.4161/onci.29125. eCollection 2014. Oncoimmunology. 2014. PMID: 25083330 Free PMC article.
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