Balaggan K - Search Results

1

Long-term effect of gene therapy on Leber's congenital amaurosis.

Bainbridge JW, Mehat MS, Sundaram V, Robbie SJ, Barker SE, Ripamonti C, Georgiadis A, Mowat FM, Beattie SG, Gardner PJ, Feathers KL, Luong VA, Yzer S, Balaggan K, Viswanathan A, de Ravel TJ, Casteels I, Holder GE, Tyler N, Fitzke FW, Weleber RG, Nardini M, Moore AT, Thompson DA, Petersen-Jones SM, Michaelides M, van den Born LI, Stockman A, Smith AJ, Rubin G, Ali RR. Bainbridge JW, et al. Among authors: balaggan k. N Engl J Med. 2015 May 14;372(20):1887-97. doi: 10.1056/NEJMoa1414221. Epub 2015 May 4. N Engl J Med. 2015. PMID: 25938638 Free PMC article. Clinical Trial.

2

Effect of gene therapy on visual function in Leber's congenital amaurosis.

Bainbridge JW, Smith AJ, Barker SS, Robbie S, Henderson R, Balaggan K, Viswanathan A, Holder GE, Stockman A, Tyler N, Petersen-Jones S, Bhattacharya SS, Thrasher AJ, Fitzke FW, Carter BJ, Rubin GS, Moore AT, Ali RR. Bainbridge JW, et al. Among authors: balaggan k. N Engl J Med. 2008 May 22;358(21):2231-9. doi: 10.1056/NEJMoa0802268. Epub 2008 Apr 27. N Engl J Med. 2008. PMID: 18441371 Free article. Clinical Trial.

3

Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy.

Tschernutter M, Schlichtenbrede FC, Howe S, Balaggan KS, Munro PM, Bainbridge JW, Thrasher AJ, Smith AJ, Ali RR. Tschernutter M, et al. Among authors: balaggan ks. Gene Ther. 2005 Apr;12(8):694-701. doi: 10.1038/sj.gt.3302460. Gene Ther. 2005. PMID: 15660111

4

Ocular gene delivery using lentiviral vectors.

Balaggan KS, Ali RR. Balaggan KS, et al. Gene Ther. 2012 Feb;19(2):145-53. doi: 10.1038/gt.2011.153. Epub 2011 Nov 3. Gene Ther. 2012. PMID: 22052240 Review.

5

Absence of ocular malignant transformation after sub-retinal delivery of rAAV2/2 or integrating lentiviral vectors in p53-deficient mice.

Balaggan KS, Duran Y, Georgiadis A, Thaung C, Barker SE, Buch PK, MacNeil A, Robbie S, Bainbridge JW, Smith AJ, Ali RR. Balaggan KS, et al. Gene Ther. 2012 Feb;19(2):182-8. doi: 10.1038/gt.2011.194. Epub 2011 Nov 24. Gene Ther. 2012. PMID: 22113317

6

Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice.

Barker SE, Broderick CA, Robbie SJ, Duran Y, Natkunarajah M, Buch P, Balaggan KS, MacLaren RE, Bainbridge JW, Smith AJ, Ali RR. Barker SE, et al. J Gene Med. 2009 Jun;11(6):486-97. doi: 10.1002/jgm.1327. J Gene Med. 2009. PMID: 19340848 Free PMC article.

7

Effective gene therapy with nonintegrating lentiviral vectors.

Yáñez-Muñoz RJ, Balaggan KS, MacNeil A, Howe SJ, Schmidt M, Smith AJ, Buch P, MacLaren RE, Anderson PN, Barker SE, Duran Y, Bartholomae C, von Kalle C, Heckenlively JR, Kinnon C, Ali RR, Thrasher AJ. Yáñez-Muñoz RJ, et al. Nat Med. 2006 Mar;12(3):348-53. doi: 10.1038/nm1365. Epub 2006 Feb 19. Nat Med. 2006. PMID: 16491086

8

In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration.

Buch PK, MacLaren RE, Durán Y, Balaggan KS, MacNeil A, Schlichtenbrede FC, Smith AJ, Ali RR. Buch PK, et al. Among authors: balaggan ks. Mol Ther. 2006 Nov;14(5):700-9. doi: 10.1016/j.ymthe.2006.05.019. Epub 2006 Jul 26. Mol Ther. 2006. PMID: 16872907 Free article.

9

The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice.

Georgiadis A, Tschernutter M, Bainbridge JW, Balaggan KS, Mowat F, West EL, Munro PM, Thrasher AJ, Matter K, Balda MS, Ali RR. Georgiadis A, et al. Among authors: balaggan ks. PLoS One. 2010 Dec 30;5(12):e15730. doi: 10.1371/journal.pone.0015730. PLoS One. 2010. PMID: 21209887 Free PMC article.

10

CNTF gene transfer protects ganglion cells in rat retinae undergoing focal injury and branch vessel occlusion.

MacLaren RE, Buch PK, Smith AJ, Balaggan KS, MacNeil A, Taylor JS, Osborne NN, Ali RR. MacLaren RE, et al. Among authors: balaggan ks. Exp Eye Res. 2006 Nov;83(5):1118-27. doi: 10.1016/j.exer.2006.05.019. Epub 2006 Jul 10. Exp Eye Res. 2006. PMID: 16831422

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