Darvesh S - Search Results

1

Butyrylcholinesterase-knockout reduces brain deposition of fibrillar β-amyloid in an Alzheimer mouse model.

Reid GA, Darvesh S. Reid GA, et al. Among authors: darvesh s. Neuroscience. 2015 Jul 9;298:424-35. doi: 10.1016/j.neuroscience.2015.04.039. Epub 2015 Apr 27. Neuroscience. 2015. PMID: 25931333 Free article.

2

Neurobiology of butyrylcholinesterase.

Darvesh S, Hopkins DA, Geula C. Darvesh S, et al. Nat Rev Neurosci. 2003 Feb;4(2):131-8. doi: 10.1038/nrn1035. Nat Rev Neurosci. 2003. PMID: 12563284 Review. No abstract available.

3

Selective reversible inhibition of human butyrylcholinesterase by aryl amide derivatives of phenothiazine.

Darvesh S, McDonald RS, Darvesh KV, Mataija D, Conrad S, Gomez G, Walsh R, Martin E. Darvesh S, et al. Among authors: darvesh kv. Bioorg Med Chem. 2007 Oct 1;15(19):6367-78. doi: 10.1016/j.bmc.2007.06.060. Epub 2007 Jul 6. Bioorg Med Chem. 2007. PMID: 17681768

4

Biochemical and histochemical comparison of cholinesterases in normal and Alzheimer brain tissues.

Darvesh S, Reid GA, Martin E. Darvesh S, et al. Curr Alzheimer Res. 2010 Aug;7(5):386-400. doi: 10.2174/156720510791383868. Curr Alzheimer Res. 2010. PMID: 19939227

5

Butyrylcholinesterase activity in multiple sclerosis neuropathology.

Darvesh S, Leblanc AM, Macdonald IR, Reid GA, Bhan V, Macaulay RJ, Fisk JD. Darvesh S, et al. Chem Biol Interact. 2010 Sep 6;187(1-3):425-31. doi: 10.1016/j.cbi.2010.01.037. Epub 2010 Feb 1. Chem Biol Interact. 2010. PMID: 20122907

6

Synthesis and preliminary evaluation of piperidinyl and pyrrolidinyl iodobenzoates as imaging agents for butyrylcholinesterase.

Macdonald IR, Reid GA, Joy EE, Pottie IR, Matte G, Burrell S, Mawko G, Martin E, Darvesh S. Macdonald IR, et al. Among authors: darvesh s. Mol Imaging Biol. 2011 Dec;13(6):1250-61. doi: 10.1007/s11307-010-0448-0. Mol Imaging Biol. 2011. PMID: 20976626

7

Butyrylcholinesterase is associated with β-amyloid plaques in the transgenic APPSWE/PSEN1dE9 mouse model of Alzheimer disease.

Darvesh S, Cash MK, Reid GA, Martin E, Mitnitski A, Geula C. Darvesh S, et al. J Neuropathol Exp Neurol. 2012 Jan;71(1):2-14. doi: 10.1097/NEN.0b013e31823cc7a6. J Neuropathol Exp Neurol. 2012. PMID: 22157615 Free PMC article.

8

Thioesters for the in vitro evaluation of agents to image brain cholinesterases.

Macdonald IR, Jollymore CT, Reid GA, Pottie IR, Martin E, Darvesh S. Macdonald IR, et al. Among authors: darvesh s. J Enzyme Inhib Med Chem. 2013 Jun;28(3):447-55. doi: 10.3109/14756366.2011.647008. Epub 2012 Jan 11. J Enzyme Inhib Med Chem. 2013. PMID: 22233541 Free article.

9

Cysteine thioesters as myelin proteolipid protein analogues to examine the role of butyrylcholinesterase in myelin decompaction.

Pottie IR, Higgins EA, Blackman RA, Macdonald IR, Martin E, Darvesh S. Pottie IR, et al. Among authors: darvesh s. ACS Chem Neurosci. 2011 Mar 16;2(3):151-9. doi: 10.1021/cn100090g. Epub 2010 Dec 30. ACS Chem Neurosci. 2011. PMID: 22778864 Free PMC article.

10

Butyrylcholinesterase radioligands to image Alzheimer's disease brain.

Darvesh S. Darvesh S. Chem Biol Interact. 2013 Mar 25;203(1):354-7. doi: 10.1016/j.cbi.2012.08.009. Epub 2012 Aug 19. Chem Biol Interact. 2013. PMID: 22935510

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