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Loss of FOXA1 Drives Sexually Dimorphic Changes in Urothelial Differentiation and Is an Independent Predictor of Poor Prognosis in Bladder Cancer.
Reddy OL, Cates JM, Gellert LL, Crist HS, Yang Z, Yamashita H, Taylor JA 3rd, Smith JA Jr, Chang SS, Cookson MS, You C, Barocas DA, Grabowska MM, Ye F, Wu XR, Yi Y, Matusik RJ, Kaestner KH, Clark PE, DeGraff DJ. Reddy OL, et al. Among authors: kaestner kh. Am J Pathol. 2015 May;185(5):1385-95. doi: 10.1016/j.ajpath.2015.01.014. Am J Pathol. 2015. PMID: 25907831 Free PMC article.
Foxa1 is essential for mammary duct formation.
Liu Y, Zhao Y, Skerry B, Wang X, Colin-Cassin C, Radisky DC, Kaestner KH, Li Z. Liu Y, et al. Among authors: kaestner kh. Genesis. 2016 May;54(5):277-85. doi: 10.1002/dvg.22929. Epub 2016 Mar 29. Genesis. 2016. PMID: 26919034 Free PMC article.
Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer.
Osei-Amponsa V, Buckwalter JM, Shuman L, Zheng Z, Yamashita H, Walter V, Wildermuth T, Ellis-Mohl J, Liu C, Warrick JI, Shantz LM, Feehan RP, Al-Ahmadie H, Mendelsohn C, Raman JD, Kaestner KH, Wu XR, DeGraff DJ. Osei-Amponsa V, et al. Among authors: kaestner kh. Oncogene. 2020 Feb;39(6):1302-1317. doi: 10.1038/s41388-019-1063-4. Epub 2019 Oct 21. Oncogene. 2020. PMID: 31636388
Mild nephrogenic diabetes insipidus caused by Foxa1 deficiency.
Behr R, Brestelli J, Fulmer JT, Miyawaki N, Kleyman TR, Kaestner KH. Behr R, et al. Among authors: kaestner kh. J Biol Chem. 2004 Oct 1;279(40):41936-41. doi: 10.1074/jbc.M403354200. Epub 2004 Jul 13. J Biol Chem. 2004. PMID: 15252040 Free article.
425 results