Therrien M - Search Results

1

Regulation of RAF protein kinases in ERK signalling.

Lavoie H, Therrien M. Lavoie H, et al. Among authors: therrien m. Nat Rev Mol Cell Biol. 2015 May;16(5):281-98. doi: 10.1038/nrm3979. Nat Rev Mol Cell Biol. 2015. PMID: 25907612 Review.

2

CNK, a RAF-binding multidomain protein required for RAS signaling.

Therrien M, Wong AM, Rubin GM. Therrien M, et al. Cell. 1998 Oct 30;95(3):343-53. doi: 10.1016/s0092-8674(00)81766-3. Cell. 1998. PMID: 9814705 Free article.

3

Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism.

Laberge G, Douziech M, Therrien M. Laberge G, et al. Among authors: therrien m. EMBO J. 2005 Feb 9;24(3):487-98. doi: 10.1038/sj.emboj.7600558. Epub 2005 Jan 20. EMBO J. 2005. PMID: 15660123 Free PMC article.

4

Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila.

Baril C, Therrien M. Baril C, et al. Among authors: therrien m. Dev Biol. 2006 Jun 1;294(1):232-45. doi: 10.1016/j.ydbio.2006.02.046. Epub 2006 Apr 4. Dev Biol. 2006. PMID: 16600208 Free article.

5

A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila.

Douziech M, Sahmi M, Laberge G, Therrien M. Douziech M, et al. Among authors: therrien m. Genes Dev. 2006 Apr 1;20(7):807-19. doi: 10.1101/gad.1390406. Genes Dev. 2006. PMID: 16600912 Free PMC article.

6

KSR and CNK: two scaffolds regulating RAS-mediated RAF activation.

Clapéron A, Therrien M. Clapéron A, et al. Among authors: therrien m. Oncogene. 2007 May 14;26(22):3143-58. doi: 10.1038/sj.onc.1210408. Oncogene. 2007. PMID: 17496912 Review.

7

A dimerization-dependent mechanism drives RAF catalytic activation.

Rajakulendran T, Sahmi M, Lefrançois M, Sicheri F, Therrien M. Rajakulendran T, et al. Among authors: therrien m. Nature. 2009 Sep 24;461(7263):542-5. doi: 10.1038/nature08314. Epub 2009 Sep 2. Nature. 2009. PMID: 19727074

8

[It takes two RAFs to tango].

Lavoie H, Therrien M. Lavoie H, et al. Among authors: therrien m. Med Sci (Paris). 2010 May;26(5):459-60. doi: 10.1051/medsci/2010265459. Med Sci (Paris). 2010. PMID: 20510139 Free article. French. No abstract available.

9

Mechanistic principles of RAF kinase signaling.

Udell CM, Rajakulendran T, Sicheri F, Therrien M. Udell CM, et al. Among authors: therrien m. Cell Mol Life Sci. 2011 Feb;68(4):553-65. doi: 10.1007/s00018-010-0520-6. Epub 2010 Sep 6. Cell Mol Life Sci. 2011. PMID: 20820846 Free PMC article. Review.

10

The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila.

Ashton-Beaucage D, Udell CM, Lavoie H, Baril C, Lefrançois M, Chagnon P, Gendron P, Caron-Lizotte O, Bonneil E, Thibault P, Therrien M. Ashton-Beaucage D, et al. Among authors: therrien m. Cell. 2010 Oct 15;143(2):251-62. doi: 10.1016/j.cell.2010.09.014. Cell. 2010. PMID: 20946983 Free article.

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